The role of chemistry in the development of boron neutron capture therapy of cancer
MF Hawthorne - Angewandte Chemie International Edition in …, 1993 - Wiley Online Library
A therapeutic method that selectively destroys malignant cells in the presence of normal
cells is a highly valued goal of oncologists and the possible salvation of cancer patients …
cells is a highly valued goal of oncologists and the possible salvation of cancer patients …
A critical assessment of boron target compounds for boron neutron capture therapy
M Frederick Hawthorne, MW Lee - Journal of neuro-oncology, 2003 - Springer
Boron neutron capture therapy (BNCT) has undergone dramatic developments since its
inception by Locher in 1936 and the development of nuclear energy during World War II …
inception by Locher in 1936 and the development of nuclear energy during World War II …
Determination of boron in tissues and cells using direct-current plasma atomic emission spectroscopy
RF Barth, DM Adams, AH Soloway… - Analytical …, 1991 - ACS Publications
The accurate measurement of total boron content in bio-logical samples with a sensitivity in
the ppm range is essential for evaluating the potential usefulness of various tumorlocalizing …
the ppm range is essential for evaluating the potential usefulness of various tumorlocalizing …
Response of the central nervous system to boron neutron capture irradiation: evaluation using rat spinal cord model
GM Morris, JA Coderre, JW Hopewell, PL Micca… - Radiotherapy and …, 1994 - Elsevier
The response of the central nervous system to boron neutron capture irradiation, with either
p-boronophenylalanine (BPA) or borocaptate sodium (BSH) as neutron capture agents, has …
p-boronophenylalanine (BPA) or borocaptate sodium (BSH) as neutron capture agents, has …
An analysis of the structure of the compound biological effectiveness factor
K Ono - Journal of Radiation Research, 2016 - academic.oup.com
This report is an analysis of the structure of the compound biological effectiveness (CBE)
factor. The value of the CBE factor previously reported was revalued for the central nervous …
factor. The value of the CBE factor previously reported was revalued for the central nervous …
Response of rat skin to boron neutron capture therapy with p-boronophenylalanine or borocaptate sodium
GM Morris, JA Coderre, JW Hopewell, PL Micca… - Radiotherapy and …, 1994 - Elsevier
The effects of boron neutron capture irradiation employing either BPA or BSH as neutron
capture agents has been assessed using the dorsal skin of Fischer 344 rats …
capture agents has been assessed using the dorsal skin of Fischer 344 rats …
Die Rolle der Chemie in der Entwicklung einer Krebstherapie durch die Bor‐Neutroneneinfangreaktion
MF Hawthorne - Angewandte Chemie, 1993 - Wiley Online Library
Abstract Ein Therapieverfahren, das Tumorzellen in Gegenwart gesunder Zellen selektiv
zerstört, ist das große Ziel der Onkologen und würde möglicherweise die Rettung für …
zerstört, ist das große Ziel der Onkologen und würde möglicherweise die Rettung für …
Methods for boron analysis in boron neutron capture therapy (BNCT). A review
TU Probst - Fresenius' journal of analytical chemistry, 1999 - Springer
The possibilities and limitations of the numerous individual methods used for boron analysis
for BNCT in clinical and biological samples are reported in detail. The main interferences of …
for BNCT in clinical and biological samples are reported in detail. The main interferences of …
Boron neutron capture irradiation of the rat spinal cord: histopathological evidence of a vascular-mediated pathogenesis
GM Morris, JA Coderre, A Bywaters… - Radiation …, 1996 - meridian.allenpress.com
A histopathological study was carried out on the spinal cord of rats after boron neutron
capture (BNC) irradiation. Rats were irradiated with thermal neutrons alone or in …
capture (BNC) irradiation. Rats were irradiated with thermal neutrons alone or in …
Measurement of 10B concentration through autoradiography images in polycarbonate nuclear track detectors
A Portu, OA Bernaola, S Nievas, S Liberman… - Radiation …, 2011 - Elsevier
The determination of the local concentration of boron in the different regions of tissue
samples treated by Boron Neutron Capture Therapy (BNCT) could be made through the …
samples treated by Boron Neutron Capture Therapy (BNCT) could be made through the …