Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging

PJ Gawne, F Man, PJ Blower… - Chemical reviews, 2022 - ACS Publications
The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …

Clinical experience with 99mTc-hexamethylpropylene-amineoxime for labelling leucocytes and imaging inflammation

AM Peters, S Osman, BL Henderson, JD Kelly… - The Lancet, 1986 - Elsevier
Hexamethylpropylene-amineoxime (HMPAO) forms a lipid-soluble neutral complex with
99m Tc which is rapidly incorporated into leucocytes in vitro. In six patients with suspected or …

Inflammation: imaging with Tc-99m HMPAO-labeled leukocytes.

ME Roddie, AM Peters, HJ Danpure, S Osman… - Radiology, 1988 - pubs.rsna.org
Leukocytes labeled with technetium-99m hexamethylpropyleneamine oxime (HMPAO) were
used in 100 patients: 32 with suspected inflammatory bowel disease, 17 with fever of …

[BOOK][B] Fluorine magnetic resonance imaging

U Flogel, E Ahrens - 2016 - taylorfrancis.com
Over the past decade, fluorine (19F) magnetic resonance imaging (MRI) has garnered
significant scientific interest in the biomedical research community owing to the unique …

Effects of m-chlorophenylpiperazine on regional brain glucose utilization: a positron emission tomographic comparison of alcoholic and control subjects

D Hommer, P Andreasen, D Rio… - Journal of …, 1997 - Soc Neuroscience
m-Chlorophenylpiperazine (mCPP) is a mixed serotonin agonist/antagonist used
extensively in psychiatric research. Alcoholics show blunted neuroendocrine responses to …

[PDF][PDF] In vitro and in vivo evaluation of granulocyte labeling with [99mTc] d, 1-HM-PAO

L Mortelmans, S Malbrain, J Stuyck… - Journal of nuclear …, 1989 - Soc Nuclear Med
The functional integrity of white blood cells labeled with [@ †TcJd, l-HM-PAOcontaining
variable amounts of the ligand or of the@ †œTc activity was evaluated by enzymatic tests …

Investigation of suspected intra-abdominal sepsis: the contribution of nuclear medicine

E Lantto - Scandinavian Journal of Gastroenterology, 1994 - Taylor & Francis
The diagnosis of abdominal infections and inflammations often presents considerable
difficulty, and various imaging techniques may be required to localize them accurately. At …

Radioisotopic imaging allows optimization of adenovirus lung deposition for cystic fibrosis gene therapy

S Lerondel, A Le Pape, C Sené, L Faure… - Human gene …, 2001 - liebertpub.com
Cystic fibrosis is a common, heriditary disease resulting from mutations of the cystic fibrosis
transmembrane conductance regulator (CFTR) gene. Airway transfer of the CFTR gene is a …

Phagocytic labeling of leukocytes with 99mTc-albumin colloid for nuclear imaging

CS Marcus, JH Kuperus, JA Butler… - International Journal of …, 1988 - Elsevier
A procedure is described for the phagocytic labeling of white blood cells (WBC) with high
specific activity 99m Tc-albumin colloid (TAC). The preparation contains approximately …

In vitro comparison of HMPAO and gentisic acid for labelling leukocytes with99mTc

M Ecclestone, A Proulx, JR Ballinger, B Gerson… - European journal of …, 1990 - Springer
Leukocytes can be labelled with 99m Tc using HMPAO and gentisic acid methods. We
compared the two methods with respect to labelling efficiency on mixed leukocytes and …