Radiopharmaceutical-related pitfalls and artifacts

JC Hung, JA Ponto, RJ Hammes - Seminars in nuclear medicine, 1996 - Elsevier
The primary goal of this review article is to increase the reader's knowledge and
understanding of problems associated with the radiopharmaceuticals commonly used in …

[HTML][HTML] Reappraisal of the health risks associated with the use of high doses of oral and injectable androgenic steroids

KE Friedl - NIDA Res Monogr, 1990 - books.google.com
A price is paid for a beard and the presence of functional testes. Inheritance, ageing, and
other factors determine what the cost will be to the individual.(Hamilton 1948, p. 315) Many …

Characterization of the uptake of 16α-([18F] fluoro)-17β-estradiol in DMBA-induced mammary tumors

CJ Mathias, MJ Welch, JA Katzenellenbogen… - International Journal of …, 1987 - Elsevier
In order to investigate possible correlations between the uptake of 16α-([18 F] fluoro)-17β-
estradiol (18 F-ES) by 7, 12-dimethylbenz (a) anthracene (DMBA)-induced tumors in rats …

Steroid receptor ligands for breast cancer targeting: an insight into their potential role as PET imaging agents

MC Oliveira, C Neto, G Ribeiro Morais… - Current medicinal …, 2013 - ingentaconnect.com
The design and development of radiolabelled steroid derivatives has been an important
area of research due to their wellknown value in breast cancer targeting. The estrogen …

Preparation and evaluation of 17-ethynyl-substituted 16α-[18F] fluoroestradiols: selective receptor-based PET imaging agents

HF Vanbrocklin, MG Pomper, KE Carlson… - International journal of …, 1992 - Elsevier
We have prepared and studied six new analogs of 16α-fluoroestradiol (FES): 17α-and 17β-
ethynyl-FES (7 [FEES] and 7a), and the 11β-ethyl (8 and 8a) and 11β-methoxy (9 and 9a) …

Fundamental considerations in the design of fluorine-18 labeled progestins and androgens as imaging agents for receptor-positive tumors of the breast and prostate

SJ Brandes, JA Katzenellenbogen - … . Part B. Nuclear Medicine and Biology, 1988 - Elsevier
Most efforts at developing steroid receptor-based imaging agents have, up to now, been
focused on the estrogen receptor (ER) in breast cancer. Success in this area has been very …

The pharmacology of steroid radiopharmaceuticals: specific and non-specific binding and uptake selectivity

JA Katzenellenbogen - Radiopharmaceuticals, 2018 - taylorfrancis.com
While pharmacology has traditionally been a discipline concerned with therapeutic drugs,
many parallels can be drawn between pharmacological considerations in the therapeutic …

Carbon-11-labeled estrogens as potential imaging agents for breast tumors

CS Dence, E Napolitano, JA Katzenellenbogen… - Nuclear medicine and …, 1996 - Elsevier
We have prepared two estrogens labeled with carbon-11, 17α-[11C] methylestradiol and
11β-ethyl-17α-[11C] methylestradiol, at a specific activity of 300–1000 Ci/mmol (11.1–37 …

Radioiodinated ligands for the estrogen receptor: Tissue distribution of 17α-[125I] iodovinylestradiol derivatives in normal and tumor-bearing adult female rats

RN Hanson, LA Franke, M Kaplan - … . Part B. Nuclear medicine and biology, 1990 - Elsevier
A series of three 125 I-labeled 17α-iodovinylestradiol derivatives previously demonstrated to
have a selectivity for estrogen receptor tissues in immature female rats were selected for …

Synthesis and evaluation of (17α, 20E) 21-[125I] iodo-11-substituted-19-norpregna-1, 3, 5 (10), 20-tetraene-3, 17β-diols: the influence of 11-stereochemistry on tissue …

RN Hanson, LA Franke, ML Kaplan - … . Part B. Nuclear Medicine and Biology, 1989 - Elsevier
Abstract The 21-tri-n-butylstannyl derivatives of (17α, 20E)-11α and β-methoxy-19-
norpregna-1, 3, 5 (10), 20-tetraene-3, 17β-diol were synthesized and characterized. These …