Role of radical prostatectomy in metastatic prostate cancer: a review

MJ Metcalfe, MC Smaldone, DW Lin… - … Oncology: Seminars and …, 2017 - Elsevier
Context Recent demonstration of efficacy with the use of chemohormonal therapy for men
with metastatic prostate cancer (mPCa) has expanded the therapeutic options for these …

[HTML][HTML] Role of surgery in oligometastatic prostate cancer

P Jenjitranant, KA Touijer - Prostate international, 2019 - Elsevier
Androgen deprivation therapy as single modality therapy was the standard management for
oligometastatic prostate cancer (PCa). Current paradigm shifts toward a multimodality …

Control of polyamine biosynthesis by antizyme inhibitor 1 is important for transcriptional regulation of arginine vasopressin in the male rat hypothalamus

MP Greenwood, M Greenwood, JFR Paton… - …, 2015 - academic.oup.com
The polyamines spermidine and spermine are small cations present in all living cells. In the
brain, these cations are particularly abundant in the neurons of the paraventricular (PVN) …

Differential Effect of α-Difluoromethylornithine on the in Vivo Uptake of 14C-labeled Polyamines and Methylglyoxal Bis(guanylhydrazone) by a Rat Prostate-derived …

WDW Heston, D Kadmon, DF Covey, WR Fair - Cancer research, 1984 - AACR
The uptake of exogenously administered radiolabeled polyamines by a rat prostate-derived
tumor line, the Dunning R3327 MAT-Lu, and various normal tissues was studied …

N-3-[18F] fluoropropylputrescine as potential PET imaging agent for prostate and prostate derived tumors.

DR Hwang, LX Lang, CJ Mathias… - Journal of Nuclear …, 1989 - europepmc.org
A potential PET imagining agent for prostate and prostate derived tumors, N-3-[18F]
fluoropropylputrescine, has been prepared. The radiochemical yield was 7-10% at end-of …

Potentiation of methylglyoxal‐bis‐guanylhydrazone by alpha‐difluoromethylornithine in rat prostate cancer

HW Herr, EL Kleinert, NM Relyea, WF Whitmore JR - Cancer, 1984 - Wiley Online Library
The polyamines, putrescine, spermidine, and spermine, are fundamentally related to both
normal and neoplastic cell proliferation. The prostate gland and prostatic tumors in man and …

Solid state support for the synthesis of [1− 11C]-putrescine

CW Somawardhana, M Sajjad… - International journal of …, 1991 - Elsevier
A novel solid state support was demonstrated using [11 C]-HCN for the radiosynthesis of [1−
11 C]-putrescine by the Michael addition reaction to acrylonitrile. The silica gel support …

Antigrowth effect of polyamine biosynthesis inhibitors on the Dunning R 3327‐G prostatic tumor

HW Herr, EL Kleinert - The Prostate, 1984 - Wiley Online Library
Abstract α‐Difluoromethylornithine (DFMO) and methylglyoxal‐bis‐guanylhydrazone
(MGBG), when administered simultaneously, inhibited growth and were highly toxic to the …

Carcinoma of the prostate: Diagnosis and staging: Current status and future prospects

WR Fair, D Kadmon - World Journal of Urology, 1983 - Springer
No simple screening test for prostatic cancer (CaP) is yet available. Likewise, in most cases,
accurate staging requires surgical exploration to determine nodal metastases although there …

Synthesis and uptake of no-carrier-added 1-[11C] putrescine into rat prostate

PA Jerabek, CS Dence, MR Kilbourn, MJ Welch… - International Journal of …, 1985 - Elsevier
No carrier-added 1-[11 C] putrescine has been prepared using a simple two-step procedure.
Radiochemical yields of 1–2% at end-of-synthesis were obtained in a synthesis time of 50 …