Peripheral Metabolism of Thyroid Hormones in Man, I. Direct Measurement of the Conversion Rate of Thyroxine to 3,5,3'-Triiodothyronine (T3) and Determination of the …

R Bianchi, G Mariani, N Molea, F Vitek… - The Journal of …, 1983 - academic.oup.com
We describe here a new method for the direct measurement of the conversion rate of T4 to
T3 in man. The metabolic study was performed in 23 subjects: 13 healthy controls, 7 T4 …

Distribution of subcutaneous thyroxine, triiodothyronine, and albumin in man: comparison with intravenous administration using a kinetic model

MT HAYS, RA McGUIRE - The Journal of Clinical Endocrinology …, 1980 - academic.oup.com
Distributional kinetics of radioiodinated T4 (T4*), T3 (T3*), and albumin (RISA), after
simultaneous administration by the sc and iv routes of 125I-and 131I-labeled compounds …

Thyroid hormone synthesis, plasma membrane transport and metabolism

G Hennemann, TJ Visser - Pharmacotherapeutics of the thyroid gland, 1997 - Springer
The most important iodothyronine secreted by the thyroid gland is 3, 5, 3', 5'-
tetraiodothyronine (thyroxine, T 4). Thyroxine has little, if any, biological activity, and is …

Sulfation and glucuronidation pathways of thyroid hormone metabolism

TJ Visser - Thyroid hormone metabolism: molecular biology and …, 1994 - books.google.com
Normally, the prohormone thyroxine (3, 3', 5, 5'-tetraiodothyronine, T4) is the predominant
product secreted by the thyroid follicular cells. T4 is converted in peripheral tissues by outer …

A kinetic model of human thyroid hormones and their conversion products

RA McGUIRE, MT HAYS - The Journal of Clinical Endocrinology …, 1981 - academic.oup.com
We have examined the in vivo distribution and etabolism of radiolabeled T4 and T3in 14
normal subjects using a kinetic model. Tracer amounts of\l131I T4 and\I25I T3 were injected …

The TSH receptor

M Misrahi, E Milgrom - Pharmacotherapeutics of the thyroid gland, 1997 - Springer
The thyroid-stimulating hormone (TSH) receptor (TSHR) plays a key role in the control of
thyroid growth and function. This G-protein-coupled receptor essentially activates adenylate …

Separation of Iodothyronines from Iodinated Metabolites in Serum from Reverse T3 Tracer Kinetic Studies in Man and Dog

EM Kaptein, MT Hoopes… - Hormone and …, 1989 - thieme-connect.com
Iodothyronine separation from free iodide and iodoalbumin in serial serum samples
obtained from 7 human and 5 dog studies following intravenous injection of radiolabeled …