The primary goal of this review article is to increase the reader's knowledge and
understanding of problems associated with the radiopharmaceuticals commonly used in …

Abstract Recently, technetium-99m (99m Tc) labeling of proteins through the use of a
bifunctional chelating agent (BCA) has been reported. In previous work, a BCA containing a …

This chapter summarizes the chemistry and the applications of technetium-labeled
compounds, and highlights the advances in the field and future trends. The importance of …

We have recently described a method for radiolabeling monoclonal antibodies, with metallic
radionuclides using a new chelating agent N 2 S 3. Using this chelate the monoclonal …

We have determined that reduced 99m Tc will often bind to proteins even in the presence of
DTPA at reasonable concentrations. The extent of this competition varies with the protein but …

In this study we have compared the characteristics of six labelling kits for the preparation of
technetium-99m labelled human serum albumin (99m Tc-HSA) and evaluated the …

The successful attachment of various metallic radionuclides such as 99m Tc to monoclonal
antibodies for targeting tumor tissue in vivo depends upon the development and use of …

Technetium-99m labelled red blood cells (99m Tc-RBCs) are far superior to 99m Tc-labelled
human serum albumin (99m Tc-HSA) for radionuclide ventriculography, but their labelling is …

A plethora of radiochemicals and radiopharmaceuticals have been evaluated over the last
two decades for assessing cardiac function and myocardial tissue viability and integrity …

MATERIALS AND METHODS The study group consisted of 20 patients in whom cardiac
catheterization was performed for evaluation of either coro nary artery disease, valvular …