Clinical aerosols: I. Characterization of aerosols and their diagnostic uses

RV Lourenço, E Cotromanes - Archives of internal medicine, 1982 - jamanetwork.com
• Characterization of an aerosol is of major importance for the understanding of its
pathogenic, diagnostic, or therapeutic effect. The parameters necessary for such …

Retention and intracellular distribution of instilled iron oxide particles in human alveolar macrophages

JC Lay, WD Bennett, CS Kim, RB Devlin… - American journal of …, 1998 - atsjournals.org
Bronchoalveolar lavage (BAL) was used to sample retention of particles within the alveolar
macrophage (AM) compartment at various times from 1 to 91 d following intrapulmonary …

Disruption of normal iron homeostasis after bronchial instillation of an iron-containing particle

AJ Ghio, JD Carter, JH Richards… - … of Physiology-Lung …, 1998 - journals.physiology.org
The atmosphere constitutes a prime vehicle for the movement and redistribution of metals.
Metal exposure can be associated with an oxidative stress. We tested the hypothesis that, in …

Magnetically-targeted, technetium 99m-labeled nanoparticles to the inner ear

KJ Dormer, V Awasthi, W Galbraith… - Journal of …, 2008 - ingentaconnect.com
The cochlea presents a hurdle for intravascular drug therapy because of the blood-
labyrinthine barrier that tends to exclude entry of large molecules from its vasculature …

[BOOK][B] Therapy for mucus-clearance disorders

BK Rubin, CP van der Schans - 2004 - taylorfrancis.com
This single-source reference provides an up-to-date exploration of current medications and
devices used for the clearance of mucus from the lungs while simultaneously providing the …

Nucleolipids as building blocks for the synthesis of 99m Tc-labeled nanoparticles functionalized with folic acid

K Oumzil, S Khiati, M Camplo, M Koquely… - New Journal of …, 2014 - pubs.rsc.org
The development of drug delivery nanocarriers is emerging as a promising therapeutic tool
to transport anti-cancer agents to tumors. In this contribution, preparation of nanoparticles …

Production of 99mTc-labeled iron oxide aerosols for human lung deposition and clearance studies

KA Wales, H Petrow, DB Yeates - The International Journal of Applied …, 1980 - Elsevier
Radiolabeled aerosols used in human lung deposition and clearance studies require
nontoxic particles firmly tagged with low dose isotopes. An iron oxide sol was prepared by …

Lung mucociliary transport in asymptomatic asthma: effects of inhaled histamine

CS Garrard, DJ Mussatto… - The Journal of laboratory …, 1989 - translationalres.com
Bronchial mucociliary clearance (CB) and tracheal mucus velocity (TMV) were measured
during the course of repeated inhalations of histamine in six subjects with asthma who had …

Aerosol penetration and mucociliary transport in the healthy human lung: effect of low serum theophylline levels

E Cotromanes, TR Gerrity, CS Garrard… - Chest, 1985 - Elsevier
The effect of theophylline on the penetration of an inhaled radioaerosol in the lung,
bronchial clearance, and tracheal mucociliary transport rate (TMTR) was investigated in 13 …

Multifunctional Nanoparticles for Theranostics and Imaging

X Xue, XJ Liang - Nanomedicine: Principles and Perspectives, 2014 - Springer
A nanoparticle constituted with nanoscale or nanostructured materials can be modified by
approximate 1,500 potential sites. This unique property of nanoparticle is the foundation to …