Recent advances in copper radiopharmaceuticals

G Hao, AN Singh, OK Oz, X Sun - Current …, 2011 - ingentaconnect.com
Copper has five radioisotopes (60Cu, 61Cu, 62Cu, 64Cu, and 67Cu) that can be used in
copper radiopharmaceuticals. These radioisotopes decay by mixed emissions of β+, β-, and …

Positron Emission Tomography of Copper Metabolism in the Atp7b −/− Knock-out Mouse Model of Wilson's Disease

F Peng, S Lutsenko, X Sun, O Muzik - Molecular imaging and biology, 2012 - Springer
Purpose This study aims to determine feasibility and utility of copper-64 (II) chloride (64
CuCl 2) as a tracer for positron emission tomography (PET) of copper metabolism imbalance …

Imaging Copper Metabolism Imbalance in Atp7b −/− Knockout Mouse Model of Wilson's Disease with PET-CT and Orally Administered 64CuCl2

F Peng, S Lutsenko, X Sun, O Muzik - Molecular imaging and biology, 2012 - Springer
Objectives This study aims to determine the feasibility and utility of functional imaging of
copper metabolism imbalance in Atp7b−/− knockout mouse model of Wilson's disease (WD) …

Positron emission tomography of human hepatocellular carcinoma xenografts in mice using copper (II)-64 chloride as a tracer

H Zhang, H Cai, X Lu, O Muzik, F Peng - Academic radiology, 2011 - Elsevier
RATIONALE AND OBJECTIVES: The aim of this study was to assess copper metabolism of
human hepatocellular carcinoma (HCC) with positron emission tomographic (PET) imaging …

Mouse extrahepatic hepatoma detected on MicroPET using copper (II)-64 chloride uptake mediated by endogenous mouse copper transporter 1

F Peng, J Liu, J Wu, X Lu, O Muzik - Molecular Imaging and Biology, 2005 - Springer
Purpose This study was conducted to assess the positron-emitting copper (II)-64 chloride
(64 CuCl 2) as a probe for imaging mouse extrahepatic hepatoma expressing mouse copper …

Positron emission tomography for measurement of copper fluxes in live organisms

F Peng - Annals of the New York Academy of Sciences, 2014 - Wiley Online Library
Copper is an essential nutrient for the physiology of live organisms, but excessive copper
can be harmful. Copper radioisotopes are used for measurement of copper fluxes in live …

[PDF][PDF] Copper-64 radiopharmaceuticals for PET imaging of copper trafficking in neurological disorders

JB Torres - 2017 - kclpure.kcl.ac.uk
Copper dyshomeostasis has been identified as a pathological feature of Alzheimer's
disease (AD) and Niemann-Pick disease type C1 (NPC1), as well as other neurological …