Radiolabeling of antibodies

WC Eckelman, CH Paik, RC Reba - Cancer Research, 1980 - AACR
The radiolabeling of antibodies is considered in terms of the choice of radionuclide, the
method of conjugation, and the effect of conjugation on plasma clearance. Iodination …

Differences in the sites of iodination of proteins following four methods of radioiodination

KA Krohn, LC Knight, JF Harwig, MJ Welch - Biochimica et Biophysica Acta …, 1977 - Elsevier
The rate of deiodination of radioiodinated proteins varies with the method of iodination. To
elucidate differences in the iodinated protein labeled by various methods, we have …

[BOOK][B] Iodine labeled plasma proteins

E Regoeczi - 2019 - taylorfrancis.com
First Published in 1984, this book offers comprehensive insight into iodine labelled proteins
in the blood. Carefully compiled and filled with a vast repertoire of notes, diagrams, and …

Synthesis, plasma clearance, and in vitro stability of protein containing a conjugated indium-111 chelate

CH Paik, DE Herman, WC Eckelman… - Journal of Radioanalytical …, 1980 - Springer
A new bifunctional chelating agent, N′-(p-diazoniumbenzyl)-N, NN ″, N ″-diethylenetri-
aminetetraacetic acid (DTTA) was synthesized. The compound as coupled to methyl p …

Radionuclide venography: correlation with contrast venography

UY Ryo, M Qazi… - Journal of nuclear …, 1977 - pubmed.ncbi.nlm.nih.gov
Radionuclide venography and contrast venography were performed in 47 limbs of 35
patients, and the findings were compared with respect to their location and characteristics …

Radiopharmaceuticals for thrombus detection: Selection, preparation, and critical evaluation

KA Krohn, LC Knight - Seminars in Nuclear Medicine, 1977 - Elsevier
Nearly a decade has passed since the introduction of 125 I-fibrinogen as a tracer to aid in
the clinical diagnosis of thrombosis. During this time many new radiopharmaceuticals have …

Comparison of oncophilic radiopharmaceuticals, *I‐fibrinogen, 67Ga‐ citrate, 111In‐bleomycin, and *I‐bleomycin in tumor‐bearing mice

GL Denardo, KA Krohn, SJ Denardo - Cancer, 1977 - Wiley Online Library
The pharmacokinetics of 67Ga‐citrate, 111‐bleomycin,* I‐bleomycin, and* I‐fibrinogen were
compared in a murine KHJJ tumor model in order to assess their relative potential as agents …

Tracer electrochemistry of pertechnetate: Chelation of 99mTc by EDTA after controlled-potential reduction at mercury and platinum cathodes

CD Russell, J Majerik - The International Journal of Applied Radiation and …, 1978 - Elsevier
Technetium pharmaceuticals are usually prepared by reduction of TcO 4-in the presence of
a chelating agent. As a prototype for an electrolytic method, the reduction of tracer …

Protein bromination by bromoperoxidase from Penicillus capitatus

JA Manthey, LP Hager, KD McElvany - Methods in enzymology, 1984 - Elsevier
Publisher Summary Myeloperoxidase (MPO) and bromoperoxidase (BPO), isolated from
crude algal extracts of P. capitatus, provide excellent systems for enzymatic radiolabeling of …

Effect of iodination level on the properties of radioiodinated fibrinogen

SSL Harwig, JF Harwig, RE Coleman, MJ Welch - Thrombosis Research, 1975 - Elsevier
The effect of iodination level on the biological clearance of radioiodinated fibrinogen was
investigated. Canine, human and rabbit fibrinogen were included in the study to also test for …