Patterns, variants, artifacts, and pitfalls in conventional radionuclide bone imaging and SPECT/CT

G Gnanasegaran, G Cook, K Adamson… - Seminars in nuclear …, 2009 - Elsevier
Bone scintigraphy is one of the most common investigations performed in nuclear medicine
and is used routinely in the evaluation of patients with cancer for suspected bone …

Bone scanning: radionuclidic reaction mechanisms

AG Jones, MD Francis, MA Davis - Seminars in nuclear medicine, 1976 - Elsevier
One of the major successes of nuclear medicine in recent years has been the clinical utility
of the 99m Tc-Tabeled bone-imaging agents. This article is concerned with the evidence …

Sites and mechanisms of localization of technetium-99m phosphorus radiopharmaceuticals in acute myocardial infarcts and other tissues

LM Buja, AJ Tofe, PV Kulkarni… - The Journal of …, 1977 - Am Soc Clin Investig
This study was performed to elucidate the localization at the cellular level of technetium-99m
phosphorus (99mTc-P) radiopharmaceuticals in acute myocardial infarcts and the …

Diagnostic tests for intestinal ischemia

B Kurland, LJ Brandt, HM Delany - Surgical Clinics of North America, 1992 - Elsevier
Mesenteric ischemia is a devastating disease. Only by making an earlier diagnosis can
patient survival rate be improved. Many different modalities, including serum biochemical …

Skeletal uptake of diphosphonate: a review

I Fogelman - European journal of nuclear medicine, 1980 - Springer
The diphosphonates are currently the skeletal imaging agents of choice and while extremely
sensitive for bony abnormality their mechanism of action remains poorly understood. The …

Drug-induced changes in the biologic distribution of radiopharmaceuticals

WB Hladik III, KK Nigg, BA Rhodes - Seminars in nuclear medicine, 1982 - Elsevier
Many pharmacologic agents modify the expected distribution of radiopharmaceuticals. The
authors have attempted to synthesize the literature to date relating to drug …

Radionuclide imaging of nonneoplastic soft tissue disorders

DR Brill - Seminars in nuclear medicine, 1981 - Elsevier
In the decade since the introduction of the first 99m Tc phosphates, bone imaging has
become a popular diagnostic tool. Early on, it became apparent that many tissues other than …

[HTML][HTML] 99mTC-Methylene diphosphonate uptake at injury site correlates with osteoblast differentiation and mineralization during bone healing in mice

ZA Zhong, A Peck, S Li, J VanOss, J Snider… - Bone Research, 2015 - nature.com
Abstract 99m Tc-Methylene diphosphonate (99m Tc-MDP) is widely used in clinical settings
to detect bone abnormalities. However, the mechanism of 99m Tc-MDP uptake in bone is …

[PDF][PDF] Uptake and biodistribution of technetium-99m-MD32P during rat tibial bone repair

Z Schwartz, J Shani, WA Soskolne… - Journal of Nuclear …, 1993 - Soc Nuclear Med
In a previous study from this laboratory using this model, the incorporation of three different
99mTc@ labeledphos phates was studied and correlated with the incorporation of 47Caand …

[PDF][PDF] Blood flow and tracer uptake in normal and abnormal canine bone: comparisons with Sr-85 microspheres, Kr-81m, and Tc-99m MDP

JP Lavender, RAA Khan… - Journal of Nuclear …, 1979 - Soc Nuclear Med
Bone scanning with technetium-labeled diphos phonate compounds is used increasingly as
an aid to medical diagnosis. Various factors have been suggested as determinants of the …