Chemistry and structure–activity relationships of psychedelics

DE Nichols - Behavioral Neurobiology of Psychedelic Drugs, 2018 - Springer
This chapter will summarize structure–activity relationships (SAR) that are known for the
classic serotonergic hallucinogens (aka psychedelics), focusing on the three chemical types …

[HTML][HTML] Molecular and functional imaging studies of psychedelic drug action in animals and humans

P Cumming, M Scheidegger, D Dornbierer, M Palner… - Molecules, 2021 - mdpi.com
Hallucinogens are a loosely defined group of compounds including LSD, N, N-
dimethyltryptamines, mescaline, psilocybin/psilocin, and 2, 5-dimethoxy-4 …

Structure–activity relationships of serotonin 5‐HT2A agonists

DE Nichols - Wiley Interdisciplinary Reviews: Membrane …, 2012 - Wiley Online Library
Of the 14 known types of serotonin receptors one of the most extensively studied is the 5‐
HT2A (5‐hydroxytryptamine) receptor. In the brain, this receptor plays a key role in …

Psychotomimetic drugs: Structure-activity relationships

AT Shulgin - Stimulants, 1978 - Springer
The field of psychopharmacology has its sources in a number of different medical disciplines
involved with the function of the brain. In the area of pharmacology, a major contribution has …

Bromine-77 and iodine-123 radiopharmaceuticals

G Stöcklin - The International Journal of Applied Radiation and …, 1977 - Elsevier
The neutron deficient isotopes bromine-77 (T 1 2= 56 hr and particularly iodine-123 (T 1 2=
13.3 hr have the decay properties required for diagnostic in vivo studies. Among the …

Radiobromine and radioiodine for medical applications

DS Wilbur, MJ Adam - Radiochimica Acta, 2019 - degruyter.com
The halogens bromine and iodine have similar chemical properties and undergo similar
reactions due to their closeness in Group 17 of the periodic chart. There are a number of …

Common receptors for hallucinogens in rat brain: a comparative autoradiographic study using [125I] LSD and [125I] DOI, a new psychotomimetic radioligand

DJ McKenna, AJ Nazarali, AJ Hoffman, DE Nichols… - Brain research, 1989 - Elsevier
The S and R enantiomers of the psychotomimetic 5HT 2 agonist DOI (2, 5-dimethoxy-4-
iodophenylisopropylamine) were labeled with 125 I at high-specific activity. The regional …

The reactions 77Se (p, n) and 78Se (p, 2n) as production routes for 77Br

AGM Janssen, RLP Van Den Bosch… - … International Journal of …, 1980 - Elsevier
Yield curves were measured for the 77 Se (p, n) 77 Br reaction and the 78 Se (p, 2n) 77 Br
reaction involving isotopically enriched selenium targets. Also the contamination levels due …

Acute toxicity and gross behavioral effects of amphetamine, four methoxyamphetamines, and mescaline in rodents, dogs, and monkeys

WM Davis, JA Bedford, JL Buelke, MM Guinn… - Toxicology and applied …, 1978 - Elsevier
Mescaline (MES) and d-amphetamine (AMP) served as reference agents in a study of acute
toxic and behavioral effects of four methoxy derivatives of AMP: dl-4-methoxyamphetamine …

76Br and 77Br from decay of cyclotron produced 76Kr and 77Kr

D De Jong, H Kooiman, JT Veenboer - The International Journal of Applied …, 1979 - Elsevier
76Br and “Br from decay of cyclotron produced 76Kr and “Kr Page 1 oO?O-7OXX.7').,?01-07X6502.00
0 76Br and “Br from decay of cyclotron produced 76Kr and “Kr D. DE JONG, H. KOOIMAN and …