Drug targeting is a phenomenon which maneuvers the distribution of drug in the body in
such a manner that the major fraction of the drug interacts exclusively with the target tissue …

Controlled drug delivery including drug targeting are topics attracting increasing attention.
They are of high interest for the delivery of drugs with major side effects (eg cytotoxics …

Diagnostic radiopharmaceuticals used in nuclear medicine can cause adverse events.
Information on these adverse events is available in case reports and databases but may not …

After outlining the criteria of an ideal solid colloidal drug delivery system, a review is made
under 5 headings of the various systems described in the literature. None of these systems …

This chapter provides an overview of the techniques to produce nanoparticles and
nanocapsules, and to classify them based on the polymer properties and their ability to …

Nanoparticles and microspheres made from human serum albumin are biodegradable and,
as a physiological material, less cytocidal than cyanoacrylates. Therefore, they should be a …

Albumin microspheres are colloidal particles which are known to sustain the release of
entrapped therapeutic agent (s). The rate at which these particles metabolise in vivo can be …

This chapter is concerned primarily with somewhat larger microspheres designed to be
administered subcutaneously, intramuscularly, intravenously or intra-arterially. It highlights …

72Theoretically, a diseased body compartment can be treated by administration of relevant
drug into that biological unit; however, use of any conventional route of drug administration …

This review covers the side effects and adversereactions to radiopharmaceuticals that were
reported in the literature over the past 25 years. The information published prior to 1970 is …