The use of 99m Tc-labeled phosphate and phosphonate compounds in place of 18 F, 85 Sr,
and 87m Sr for bone scintigraphy has become commonplace throughout the world in a …

Sickling of erythrocytes in patients with S-hemoglobin causes marrow and bone infarction.
The former can be demonstrated as a lack of 99m Tc-sulfur colloid uptake on marrow …

The bone scan is generally recognized to be an extremely powerful investigational tool in
the evaluation of patients with skeletal disease. Currently 99m Tc-methylene diphosphonate …

A comprehensive review on technetium chemistry and technetium radiopharmaceuticals
was published by Deutsch et al.(1983) and the chemistry of technetium in its IV states was …

RESULTS Using the above radiographie procedures as the criteria for a diagnosis of
abnormality, 81 normal and 38 abnormal cases were found in the 119 cases studied (Table …

During the past few years there has been some evidence that earlier diagnosis of the
presence and the extent of malignant disease may lead to more rationaI treatment, with an …

The radiochemical purity of preparations for 99m Tc-bone-scanning was tested using thin-
layer chromatography and electrophoresis. The investigation included ten commercial kits …

Bone scanning has changed the management of patients and has increased the
understanding of a number of diseases affecting the skeleton. Early diagnosis of benign and …

The earliest indication that radionuclides could accumulate in the skeleton originated from
observations in painters of luminous watch dials who developed bone necrosis …

The ability to image the skeleton by bone scanning, with its sensitivity for disease, is a
relatively recent phenomenon and dates back to the development of 99m Tc-labelled …