11 C [double bond, length as m-dash] O bonds made easily for positron emission tomography radiopharmaceuticals
The positron-emitting radionuclide carbon-11 (11C, t1/2= 20.3 min) possesses the unique
potential for radiolabeling of any biological, naturally occurring, or synthetic organic …
potential for radiolabeling of any biological, naturally occurring, or synthetic organic …
[11C]HCN Radiochemistry: Recent Progress and Future Perspectives
Y Xu, W Qu - European Journal of Organic Chemistry, 2021 - Wiley Online Library
Positron emission tomography (PET) is a unique non‐invasive imaging tool for studying in
vivo biological processes. It utilizes short‐lived positron emitter labeled organic molecules to …
vivo biological processes. It utilizes short‐lived positron emitter labeled organic molecules to …
The production of ultra high activity 11C-labeled hydrogen cyanide, carbon dioxide, carbon monoxide and methane via the 14N (p, α) 11C reaction (XV)
DR Christman, RD Finn, KI Karlstrom… - The International Journal of …, 1975 - Elsevier
The use of N 2 O 2 or N 2 H 2 pressurized gaseous systems as targets in proton
bombardment makes use of the 14 N (p, α) 11 C reaction and allows the facile, quantitative …
bombardment makes use of the 14 N (p, α) 11 C reaction and allows the facile, quantitative …
Radiolabeling with [11C] HCN for positron emission tomography
YP Zhou, KJ Makaravage, P Brugarolas - Nuclear medicine and biology, 2021 - Elsevier
Hydrogen cyanide (HCN) is a versatile synthon for generating carbon‑carbon and carbon-
heteroatom bonds. Unlike other one-carbon synthons (ie, CO, CO 2), HCN can function as a …
heteroatom bonds. Unlike other one-carbon synthons (ie, CO, CO 2), HCN can function as a …
[HTML][HTML] Rapid 'on-column'preparation of hydrogen [11 C] cyanide from [11 C] methyl iodide via [11 C] formaldehyde
T Kikuchi, M Ogawa, T Okamura, AD Gee… - Chemical Science, 2022 - pubs.rsc.org
Hydrogen [11C] cyanide ([11C] HCN) is a versatile 11C-labelling agent for the production of
11C-labelled compounds used for positron emission tomography (PET). However, the …
11C-labelled compounds used for positron emission tomography (PET). However, the …
Carbon-11 and radiopharmaceuticals
AP Wolf, CS Redvanly - The International Journal of Applied Radiation and …, 1977 - Elsevier
* By acceptance of this article, the publisher and/or recipient acknowledges the US
Government's right to retain a non-exclusive, royalty-free license in and to any copyright …
Government's right to retain a non-exclusive, royalty-free license in and to any copyright …
Synthesis of carbon-11, fluorine-18, and nitrogen-13 labeled radiotracers for biomedical applications
JS Fowler, AP Wolf - 1981 - osti.gov
A number of reviews, many of them recent, have appeared on various aspects of/sup
11/C,/sup 18/F and/sup 13/N-labeled radiotracers. This monograph treats the topic …
11/C,/sup 18/F and/sup 13/N-labeled radiotracers. This monograph treats the topic …
Radiochemistry with carbon‐11
S Thompson, S Kealey, SM Sephton… - Handbook of …, 2020 - Wiley Online Library
Carbon‐11 decays into stable boron‐11 and has a physical half‐life of 20.4 minutes. The
emergence of medical cyclotrons in the 1960s and positron emission tomography in the late …
emergence of medical cyclotrons in the 1960s and positron emission tomography in the late …
[HTML][HTML] Gas Phase Transformations in Carbon-11 Chemistry
The short-lived positron-emitter carbon-11 (t 1/2= 20.4 min; β+, 99.8%) is prominent for
labeling tracers for use in biomedical research with positron emission tomography (PET) …
labeling tracers for use in biomedical research with positron emission tomography (PET) …
An efficient and practical synthesis of [2-11 C] indole via superfast nucleophilic [11 C] cyanation and RANEY® Nickel catalyzed reductive cyclization
SJ Lee, JS Fowler, D Alexoff, M Schueller… - Organic & …, 2015 - pubs.rsc.org
A rapid method for the synthesis of carbon-11 radiolabeled indole was developed using a
sub-nanomolar quantity of no-carrier-added [11C] cyanide as radio-precursor. Based upon a …
sub-nanomolar quantity of no-carrier-added [11C] cyanide as radio-precursor. Based upon a …