Adrenal imaging agents: rationale, synthesis, formulation and, metabolism

WH Beierwaltes, DM Wieland, T Yu… - Seminars in nuclear …, 1978 - Elsevier
In this introductory paper on radionuclide adrenal imaging, the rationale, synthesis,
formulation, and metabolism of two clinically well-established and one promising …

A Standardized Method for In Vivo Mouse Pancreas Imaging and Semiquantitative β Cell Mass Measurement by Dual Isotope SPECT

I Mathijs, C Xavier, C Peleman, V Caveliers… - Molecular imaging and …, 2015 - Springer
Purpose In order to evaluate future β cell tracers in vivo, we aimed to develop a
standardized in vivo method allowing semiquantitative measurement of a prospective β cell …

Evaluation of carbon-11 labelled phenylglycine and phenylalanine for pancreas scintigraphy

W Vaalburg… - Nuklearmedizin …, 1975 - thieme-connect.com
Carbon-11 (t ½= 20.4 min, β+) labelled DL-α-phenylalanine and DL-α-phenylglycine were
administered intravenously to rats and the distribution of the radioactive amino acids over …

Pancreatic scanning

JE Agnew, M Maze, CJ Mitchell - The British Journal of …, 1976 - birpublications.org
The 75Se-selenomethionine pancreas scan cannot differentiate between chronic
pancreatitis and carcinoma of the pancreas and may—although chiefly in certain defined …

[PDF][PDF] Human pancreas scintigraphy using iodine-123-labeled HIPDM and SPECT

K Yamamoto, T Shibata, H Saji, S Kubo… - Journal of Nuclear …, 1990 - Soc Nuclear Med
123-LabeledHIPDM and SPECT Page 1 HIPDMto the pancreasalso has been observedin dog
studies. The results of animal studies suggest the possi bility that this compound might be used …

Investigations of 18F—p—fluorophenylalanine for pancreas scanning

MF Cottrall, DM Taylor… - The British Journal of …, 1973 - birpublications.org
Studies of the distribution of p-fluorophenylalanine-(14C) and p-fluorophenylalanine-
(18F)(18F-pFPA) in rat tissues showed pancreas/liver concentration ratios of up to 7· 4: 1 at …

Tumor-localizing agents X: radioiodinated hypoglycemic agents

GN Holcomb, CM Boyd, RE Counsell… - Journal of …, 1971 - Elsevier
This study was undertaken to find a pancreas-specific photoscanning agent. 1-(p-
Iodobenzenesulfonyl)-3-n-propylurea-125 I was synthesized for this purpose, since it …

Biochemical and pharmacological rationales in radiotracer design

RE Counsell, N Korn - Principles Of Radiopharmacolgy, 2019 - taylorfrancis.com
This chapter focuses on the design of radiotracers used as organ-imaging or scanning
agents. The availability of new radiotracers and the development of sensitive detecting …

Synthesis and biological distribution of radiolabeled ammineruthenium (III)-amino acid complexes as potential pancreatic imaging agents

CD Meyer, MA Davis, CJ Periana - Journal of Medicinal Chemistry, 1983 - ACS Publications
Complexes of ammine [103Ru] ruthenium (III) with L-histidine,/3-(4-pyridyl)-a-alanine, and S-
[ß-(4-pyridyl) ethyl]-L-cysteine were synthesized in low specific activity and evaluated in …

A synthesis of 128Ip-iodophenylalanine

P Gielow - International Journal of Applied Radiation and Isotopes, 1977 - inis.iaea.org
[en] A synthesis of 128 Ip-Iodophenylalanine based on a Sandmeyer reaction is described.
In this method p-(2, 2-dicarbethoxy-2-acetamidoethyl)-phenyldiazonium-chloride, reacts with …