Objective Oncogenic Kras-activated robust Mek/Erk signals phosphorylate to the tuberous
sclerosis complex (Tsc) and deactivates mammalian target of rapamycin (mTOR) suppression …

Objective The initial steps of pancreatic regeneration versus carcinogenesis are insufficiently
understood. Although a combination of oncogenic Kras and inflammation has been shown …

Background Pancreatic adenocarcinoma (PDAC) is one of the most fatal malignancies.
Surgical resection supplemented by chemotherapy remains the major therapeutic regimen, but …

Background & Aims Although nearly half of pancreatic ductal adenocarcinoma (PDAC)
patients have diabetes mellitus with episodes of hyperglycemia, its tumor microenvironment is …

Measurement of cellular tracer uptake is widely applied to learn the physiologic status of cells
and their interactions with imaging agents and pharmaceuticals. In-culture measurements …

Pancreatitis is a significant risk factor for pancreatic ductal adenocarcinoma (PDAC).
Previous studies in mice have demonstrated that pancreatitis contributes to oncogenic Kras‐driven …

Objective: This study explored the relationship between the activation of the jak/stat3
signaling pathway and the CSN5 gene transcript and protein expression levels in the …

Background Transpathology highlights the interpretation of the underlying physiology behind
molecular imaging. However, it remains challenging due to the discrepancies between in …

1062 Objectives Capturing cellular adaptation under interventions may give insight in tumor
biology and therapy. However, noise in the measurements prevents the online modeling in …

B cell maturation antigen (BCMA) is an ideal target for precise treatment due to its highly
selective expression on malignant myeloma cells. This review summarizes briefly the advances …