User profiles for Zhen Cheng

Zhen Cheng

- Verified email at stanford.edu - Cited by 28320

Zhen Cheng

- Verified email at simm.ac.cn - Cited by 27230

First-in-human liver-tumour surgery guided by multispectral fluorescence imaging in the visible and near-infrared-I/II windows

…, P He, X Xia, Y Chen, SS Gambhir, Z Cheng… - Nature biomedical …, 2020 - nature.com
The second near-infrared wavelength window (NIR-II, 1,000–1,700 nm) enables fluorescence
imaging of tissue with enhanced contrast at depths of millimetres and at micrometre-scale …

A small-molecule dye for NIR-II imaging

AL Antaris, H Chen, K Cheng, Y Sun, G Hong, C Qu… - Nature materials, 2016 - nature.com
Fluorescent imaging of biological systems in the second near-infrared window (NIR-II) can
probe tissue at centimetre depths and achieve micrometre-scale resolution at depths of …

[PDF][PDF] In vitro and in vivo uncaging and bioluminescence imaging by using photocaged upconversion nanoparticles

…, C Wang, X Teng, K Cheng, Z Cheng… - Angewandte Chemie …, 2012 - personal.ntu.edu.sg
High temporal and spatial regulation of cellular activities, biological pathways, and gene
expression is critical in complex biological processes.[1] One remarkable technique that …

Crucial breakthrough of second near-infrared biological window fluorophores: design and synthesis toward multimodal imaging and theranostics

S He, J Song, J Qu, Z Cheng - Chemical Society Reviews, 2018 - pubs.rsc.org
The development of fluorophores and molecular probes for the second near-infrared biological
window (NIR-II, 1000–1700 nm) represents an important, newly emerging and dynamic …

Near-Infrared Fluorescent RGD Peptides for Optical Imaging of Integrin αvβ3 Expression in Living Mice

Z Cheng, Y Wu, Z Xiong, SS Gambhir… - Bioconjugate …, 2005 - ACS Publications
Near-infrared fluorescence optical imaging is a powerful technique for studying diseases at
the molecular level in preclinical models. We recently reported that monomeric RGD peptide …

Diverse applications of nanomedicine

…, WCW Chan, C Chen, X Chen, X Chen, Z Cheng… - ACS …, 2017 - ACS Publications
The design and use of materials in the nanoscale size range for addressing medical and
health-related issues continues to receive increasing interest. Research in nanomedicine …

[HTML][HTML] A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)

YH Jin, L Cai, ZS Cheng, H Cheng, T Deng… - Military medical …, 2020 - Springer
In December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province;
and then named “2019 novel coronavirus (2019-nCoV)” by the World Health Organization (…

[HTML][HTML] A high quantum yield molecule-protein complex fluorophore for near-infrared II imaging

…, M Zhu, K Cheng, X Hong, H Dai, Z Cheng - Nature …, 2017 - nature.com
Fluorescence imaging in the second near-infrared window (NIR-II) allows visualization of
deep anatomical features with an unprecedented degree of clarity. NIR-II fluorophores draw …

Engineered knottin peptides: a new class of agents for imaging integrin expression in living subjects

RH Kimura, Z Cheng, SS Gambhir, JR Cochran - Cancer research, 2009 - AACR
There is a critical need for molecular imaging agents to detect cell surface integrin receptors
that are present in human cancers. Previously, we used directed evolution to engineer …

microPET imaging of glioma integrin αvβ3 expression using 64Cu-labeled tetrameric RGD peptide

Y Wu, X Zhang, Z Xiong, Z Cheng… - Journal of Nuclear …, 2005 - Soc Nuclear Med
Integrin α v β 3 plays a critical role in tumor-induced angiogenesis and metastasis and has
become a promising diagnostic indicator and therapeutic target for various solid tumors. …