User profiles for Yu-Shin Ding
 | Yu-Shin Dingprofessor, NYU school of medicine Verified email at nyumc.org Cited by 25068 |
Distribution volume ratios without blood sampling from graphical analysis of PET data
The distribution volume ratio (DVR), which is a linear function of receptor availability, is widely
used as a model parameter in imaging studies. The DVR corresponds to the ratio of the …
used as a model parameter in imaging studies. The DVR corresponds to the ratio of the …
Association of dopamine transporter reduction with psychomotor impairment in methamphetamine abusers
OBJECTIVE: Methamphetamine is a popular and highly addictive drug of abuse that has raised
concerns because it has been shown in laboratory animals to be neurotoxic to dopamine …
concerns because it has been shown in laboratory animals to be neurotoxic to dopamine …
Association between decline in brain dopamine activity with age and cognitive and motor impairment in healthy individuals
OBJECTIVE: Although it is documented that brain dopamine activity declines with age, the
functional significance of this is not known. This study assessed the relation between …
functional significance of this is not known. This study assessed the relation between …
[PDF][PDF] Therapeutic doses of oral methylphenidate significantly increase extracellular dopamine in the human brain
…, M Gerasimov, L Maynard, YS Ding… - The Journal of …, 2001 - Soc Neuroscience
Methylphenidate (Ritalin) is the most commonly prescribed psychoactive drug in children for
the treatment of attention deficit hyperactivity disorder (ADHD), yet the mechanisms …
the treatment of attention deficit hyperactivity disorder (ADHD), yet the mechanisms …
Dopamine transporter occupancies in the human brain induced by therapeutic doses of oral methylphenidate
Objective:The therapeutic effects of methylphenidate in the treatment of attention deficit disorder
have been attributed to its ability to increase the synaptic concentration of dopamine by …
have been attributed to its ability to increase the synaptic concentration of dopamine by …
Loss of dopamine transporters in methamphetamine abusers recovers with protracted abstinence
Methamphetamine is a popular drug of abuse that is neurotoxic to dopamine (DA) terminals
when administered to laboratory animals. Studies in methamphetamine abusers have also …
when administered to laboratory animals. Studies in methamphetamine abusers have also …
Is methylphenidate like cocaine?: Studies on their pharmacokinetics and distribution in the human brain
Background: The purposes of this study were to investigate the pharmacokinetics of
methylphenidate hydrochloride (Ritalin) in the human brain, to compare them with those of cocaine, …
methylphenidate hydrochloride (Ritalin) in the human brain, to compare them with those of cocaine, …
Decreases in dopamine receptors but not in dopamine transporters in alcoholics
…, J Logan, R Hitzemann, YS Ding… - Alcoholism: Clinical …, 1996 - Wiley Online Library
It has been hypothesized that ethanol's actions on the dopamine (DA) system may participate
in addiction. The purpose of this study was to evaluate the DA system in the brain of …
in addiction. The purpose of this study was to evaluate the DA system in the brain of …
Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: possible contributing factors
Dopamine's role in inhibitory control is well recognized and its disruption may contribute to
behavioral disorders of discontrol such as obesity. However, the mechanism by which …
behavioral disorders of discontrol such as obesity. However, the mechanism by which …
“Nonhedonic” food motivation in humans involves dopamine in the dorsal striatum and methylphenidate amplifies this effect
The drive for food is one of the most powerful of human and animal behaviors. Dopamine, a
neurotransmitter involved with motivation and reward, its believed to regulate food intake in …
neurotransmitter involved with motivation and reward, its believed to regulate food intake in …