Brown adipose tissue (BAT) is known to function in the dissipation of chemical energy in
response to cold or excess feeding, and also has the capacity to modulate energy balance. To …

Obesity develops when energy intake exceeds energy expenditure. Although most current
obesity therapies are focused on reducing calorific intake, recent data suggest that increasing …

Maintenance of body temperature is essential for the survival of homeotherms. Brown adipose
tissue (BAT) is a specialized fat tissue that is dedicated to thermoregulation 1 . Owing to …

Background Obesity results from an imbalance between energy intake and expenditure. In
rodents and newborn humans, brown adipose tissue helps regulate energy expenditure by …

Brown adipose tissue (BAT) dissipates energy as heat to maintain optimal thermogenesis
and to contribute to energy expenditure in rodents and possibly humans. The energetic …

The development of obesity not only depends on the balance between food intake and caloric
utilization but also on the balance between white adipose tissue, which is the primary site …

The imbalance between energy intake and expenditure is the underlying cause of the
current obesity and diabetes pandemics. Central to these pathologies is the fat depot: white …

Brown adipose tissue (BAT) and beige adipose tissue combust fuels for heat production in
adult humans, and so constitute an appealing target for the treatment of metabolic disorders …

Recent findings have demonstrated that mitochondria can be transferred between cells to
control metabolic homeostasis. Although the mitochondria of brown adipocytes comprise a …

Adipose tissue is central to the regulation of energy balance. Two functionally different types
of fat are present in mammals: white adipose tissue, the primary site of triglyceride storage, …