User profiles for Yoshimasa Tanaka
 | Yoshimasa TanakaNagasaki University Verified email at nagasaki-u.ac.jp Cited by 21055 |
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
PD-1 is a receptor of the Ig superfamily that negatively regulates T cell antigen receptor
signaling by interacting with the specific ligands (PD-L) and is suggested to play a role in the …
signaling by interacting with the specific ligands (PD-L) and is suggested to play a role in the …
Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice
Dilated cardiomyopathy is a severe pathology of the heart with poorly understood etiology.
Disruption of the gene encoding the negative immunoregulatory receptor PD-1 in BALB/c …
Disruption of the gene encoding the negative immunoregulatory receptor PD-1 in BALB/c …
Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer
The ligands for programmed cell death 1 (PD-1), an immunoinhibitory receptor belonging to
CD28/cytotoxic T lymphocyte antigen 4 family, are PD-1 ligand 1 and 2 (PD-Ls). Recent …
CD28/cytotoxic T lymphocyte antigen 4 family, are PD-1 ligand 1 and 2 (PD-Ls). Recent …
[HTML][HTML] Risk factors contributing to type 2 diabetes and recent advances in the treatment and prevention
Y Wu, Y Ding, Y Tanaka, W Zhang - International journal of medical …, 2014 - ncbi.nlm.nih.gov
Type 2 diabetes is a serious and common chronic disease resulting from a complex
inheritance-environment interaction along with other risk factors such as obesity and sedentary …
inheritance-environment interaction along with other risk factors such as obesity and sedentary …
Natural and synthetic non-peptide antigens recognized by human γδ T cells
T LYMPHOCYTES express either αβ or γδ T-cell receptor heterodimers 1,2 . Most αβ T cells
recognize antigenic peptides bound to major histocompatibility complex molecules but the …
recognize antigenic peptides bound to major histocompatibility complex molecules but the …
Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice
We recently reported that mice deficient in the programmed cell death-1 (PD-1) immunoinhibitory
coreceptor develop autoimmune dilated cardiomyopathy (DCM), with production of high…
coreceptor develop autoimmune dilated cardiomyopathy (DCM), with production of high…
[HTML][HTML] Direct presentation of nonpeptide prenyl pyrophosphate antigens to human γδ T cells
Human Vγ2Vδ2 + T cells recognize mycobacterial non-peptide antigens, such as isopentenyl
pyrophosphate, and their synthetic analogs, such as monoethyl phosphate, through a TCR-…
pyrophosphate, and their synthetic analogs, such as monoethyl phosphate, through a TCR-…
The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors
Signaling through the programmed death 1 (PD-1) inhibitory receptor upon binding its ligand,
PD-L1, suppresses immune responses against autoantigens and tumors and plays an …
PD-L1, suppresses immune responses against autoantigens and tumors and plays an …
Nonpeptide ligands for human gamma delta T cells.
Y Tanaka, S Sano, E Nieves… - Proceedings of the …, 1994 - National Acad Sciences
gamma delta T cells respond to a variety of microbial pathogens and transformed cells. Their
limited receptor repertoire and activation by mycobacterial antigens resistant to proteases …
limited receptor repertoire and activation by mycobacterial antigens resistant to proteases …
Differential expression of PD-L1 and PD-L2, ligands for an inhibitory receptor PD-1, in the cells of lymphohematopoietic tissues
PD-1 is a member of the immunoglobulin superfamily expressed on immune cells, including
T and B cells, and is involved in the delivery of inhibitory signal upon engagement of its …
T and B cells, and is involved in the delivery of inhibitory signal upon engagement of its …