Mutation spectrum of the retinoblastoma gene in osteosarcomas

…, T Shimizu, K Ishizaki, MS Sasaki, Y Kotoura… - Cancer research, 1994 - AACR
We have performed an intensive mutation survey of the Rb gene in 63 osteosarcomas. Loss
of heterozygosity (LOH) at the Rb locus was analyzed by using polymerase chain reaction …

Mutation Spectrum of the p53 Gene in Bone and Soft Tissue Sarcomas

…, SH Dayton, GE Herrera, T Yamamuro, Y Kotoura… - Cancer research, 1992 - AACR
We present here an analysis of the spectrum of mutations of the p53 gene seen in 127 bone
and soft tissue sarcomas of various histological classifications. Gross rearrangements were …

Poly (vinyl alcohol) hydrogel as an artificial articular cartilage: evaluation of biocompatibility

…, M Oka, P Kumar, Y Kotoura… - Journal of Applied …, 1991 - Wiley Online Library
We have developed a new poly(vinyl alcohol) hydrogel (PVA‐H) of increased physical strength
through a new manufacturing process. Its mechanical properties have been found to be …

Bone‐bonding ability of P2O5‐Free CaO · SiO2 glasses

…, T Kokubo, Y Ebisawa, Y Kotoura… - Journal of …, 1991 - Wiley Online Library
An apatite‐ and wollastonite‐containing glass‐ceramic (A · W‐GC) has been reported to
form a tight bond with living bone through an apatite layer formed on its surface. This layer is …

Low wear rate of UHMWPE against zirconia ceramic (Y‐PSZ) in comparison to alumina ceramic and SUS 316L alloy

…, T Yamamuro, H Okumura, Y Kotoura - Journal of …, 1991 - Wiley Online Library
Partially stabilized zirconia ceramic is being recognized among ceramics for its high strength
and toughness. With this ceramic, is possible to manufacture a 22‐mm‐size femoral head …

Preferential mutation of paternally derived RB gene as the initial event in sporadic osteosarcoma

…, M Ikenaga, M Kato, M Sugimot, Y Kotoura… - Nature, 1989 - nature.com
SUCCESSIVE loss of function of both alleles of the retinoblastoma susceptibility gene (RB)
on human chromosome 13 seems to be critical in the development of retinoblastoma 1–3 …

A heat‐generating bioactive glass–ceramic for hyperthermia

…, Y Ebisawa, T Kokubo, Y Kotoura… - Journal of Applied …, 1991 - Wiley Online Library
Glass plates of the chemical composition: CaO (29.0), SiO 2 (31.0), Fe 2 O 3 (40.0), B 2 O 3 (3.0),
P 2 O 5 (3.0) in weight ratio were heated to 1050 C at a rate of 5 C/min and then cooled …

Chromosomal reorganization for the expression of recessive mutation of retinoblastoma susceptibility gene in the development of osteosarcoma

…, MS Sasaki, M Ikenaga, M Sugimoto, Y Kotoura… - Cancer research, 1988 - AACR
Recent evidence indicates that the mutation of retinoblastoma susceptibility (RB) gene is
also involved in the development of osteosarcoma. We studied 30 cases of osteosarcoma for …

Pulmonary cysts as the sole metastatic manifestation of soft tissue sarcoma: case report and consideration of the pathogenesis

S Hasegawa, K Inui, K Kamakari, Y Kotoura, K Suzuki… - Chest, 1999 - Elsevier
A 29-year-old woman with an unusual form of pulmonary metastasis from epithelioid
sarcoma of the right forearm is presented. Since she manifested left pneumothorax due to …

Septum-like structures in lipoma and liposarcoma: MR imaging and pathologic correlation

M Hosono, H Kobayashi, R Fujimoto, Y Kotoura… - Skeletal radiology, 1997 - Springer
Objective To investigate the septum-like structures in pre-dominantly lipomatous tumors, by
correlating fat-suppressed MR images with histopathologic findings. Design and patients …