User profiles for Yongkang Gai
 | Yongkang GaiDepartment of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong … Verified email at hust.edu.cn Cited by 1509 |
[HTML][HTML] Escherichiacoli Nissle 1917 as a Novel Microrobot for Tumor-Targeted Imaging and Therapy
Highly efficient drug delivery systems with excellent tumor selectivity and minimal toxicity to
normal tissues remain challenging for tumor treatment. Although great effort has been made …
normal tissues remain challenging for tumor treatment. Although great effort has been made …
Cyclic reactions-mediated self-supply of H2O2 and O2 for cooperative chemodynamic/starvation cancer therapy
X Zhang, C He, Y Chen, C Chen, R Yan, T Fan, Y Gai… - Biomaterials, 2021 - Elsevier
Hydroxyl radical (·OH)-mediated chemodynamic therapy (CDT) and glucose oxidase (GOx)-based
starvation therapy (ST) are two emerging antitumor strategies, limited by acid/H 2 O 2 …
starvation therapy (ST) are two emerging antitumor strategies, limited by acid/H 2 O 2 …
68Ga-DOTA-FAPI-04 PET/MR in the evaluation of gastric carcinomas: comparison with 18F-FDG PET/CT
C Qin, F Shao, Y Gai, Q Liu, W Ruan, F Liu… - Journal of Nuclear …, 2022 - Soc Nuclear Med
We sought to evaluate the performance of 68 Ga-DOTA-FAPI-04 ( 68 Ga-FAPI) PET/MR for
the diagnosis of primary tumor and metastatic lesions in patients with gastric carcinomas and …
the diagnosis of primary tumor and metastatic lesions in patients with gastric carcinomas and …
A head-to-head comparison of 68Ga-DOTA-FAPI-04 and 18F-FDG PET/MR in patients with nasopharyngeal carcinoma: a prospective study
C Qin, F Liu, J Huang, W Ruan, Q Liu, Y Gai… - European journal of …, 2021 - Springer
Purpose To conduct a head-to-head comparison of the diagnostic ability of 68 Ga-DOTA-FAPI-04
( 68 Ga-FAPI) and 18 F-FDG PET/MR in nasopharyngeal carcinoma (NPC) patients. …
( 68 Ga-FAPI) and 18 F-FDG PET/MR in nasopharyngeal carcinoma (NPC) patients. …
[HTML][HTML] Co-delivery of doxorubicin and Bmi1 siRNA by folate receptor targeted liposomes exhibits enhanced anti-tumor effects in vitro and in vivo
T Yang, B Li, S Qi, Y Liu, Y Gai, P Ye, G Yang… - Theranostics, 2014 - ncbi.nlm.nih.gov
Bmi1 gene overexpression is found in various human tumors and has been shown as a
potential target for gene treatment. However, siRNA-based treatments targeting Bmi1 gene have …
potential target for gene treatment. However, siRNA-based treatments targeting Bmi1 gene have …
Red blood cell membrane-coated upconversion nanoparticles for pretargeted multimodality imaging of triple-negative breast cancer
M Li, H Fang, Q Liu, Y Gai, L Yuan, S Wang, H Li… - Biomaterials …, 2020 - pubs.rsc.org
Upconversion nanoparticles (UCNPs) have been widely employed for tumor imaging using
magnetic resonance imaging (MRI) and upconversion luminescence (UCL) imaging. The …
magnetic resonance imaging (MRI) and upconversion luminescence (UCL) imaging. The …
A solid lipid coated calcium peroxide nanocarrier enables combined cancer chemo/chemodynamic therapy with O2/H2O2 self-sufficiency
…, X Zhang, C Chen, X Liu, Y Chen, R Yan, T Fan, Y Gai… - Acta biomaterialia, 2021 - Elsevier
The unfavorable factors in tumor microenvironment such as hypoxia and limited H 2 O 2
levels greatly impede the anticancer efficacy of chemotherapy and chemodynamic therapy (CDT…
levels greatly impede the anticancer efficacy of chemotherapy and chemodynamic therapy (CDT…
[HTML][HTML] Ultra-sensitive nanoprobe modified with tumor cell membrane for UCL/MRI/PET multimodality precise imaging of triple-negative breast cancer
H Fang, M Li, Q Liu, Y Gai, L Yuan, S Wang, X Zhang… - Nano-micro letters, 2020 - Springer
Triple-negative breast cancer (TNBC) is a subtype of breast cancer in which the estrogen
receptor and progesterone receptor are not expressed, and human epidermal growth factor …
receptor and progesterone receptor are not expressed, and human epidermal growth factor …
[HTML][HTML] Extracellular vesicles-based pre-targeting strategy enables multi-modal imaging of orthotopic colon cancer and image-guided surgery
Backgroud Colon cancer contributes to high mortality rates as the result of incomplete
resection in tumor surgery. Multimodal imaging can provide preoperative evaluation and …
resection in tumor surgery. Multimodal imaging can provide preoperative evaluation and …
68Ga-FAPI PET visualize heart failure: from mechanism to clinic
W Song, X Zhang, SK He, Y Gai, C Qin, F Hu… - European Journal of …, 2023 - Springer
Purpose Heart failure (HF) is a chronic progressive clinical syndrome associated with structural
and/or functional heart abnormalities. Active fibroblasts and ventricular remodelling play …
and/or functional heart abnormalities. Active fibroblasts and ventricular remodelling play …