Loihi: A neuromorphic manycore processor with on-chip learning

…, A Paul, J Tse, G Venkataramanan, YH Weng… - Ieee …, 2018 - ieeexplore.ieee.org
Loihi is a 60-mm2 chip fabricated in Intels 14-nm process that advances the state-of-the-art
modeling of spiking neural networks in silicon. It integrates a wide range of novel features for …

Parkinson disease: diagnostic utility of diffusion kurtosis imaging

JJ Wang, WY Lin, CS Lu, YH Weng, SH Ng, CH Wang… - Radiology, 2011 - pubs.rsna.org
Purpose To examine the usefulness of diffusion kurtosis imaging for the diagnosis of
Parkinson disease (PD). Materials and Methods Examinations were performed with the …

A common missense variant in the LRRK2 gene, Gly2385Arg, associated with Parkinson's disease risk in Taiwan

…, EJ Simons, CF Rohé, HC Chang, RS Chen, YH Weng… - neurogenetics, 2006 - Springer
Mutations in the LRRK2 gene are a cause of autosomal dominant Parkinson’s disease (PD).
Whether LRRK2 variants influence susceptibility to the commoner, sporadic forms of PD …

[HTML][HTML] PARK6 PINK1 mutants are defective in maintaining mitochondrial membrane potential and inhibiting ROS formation of substantia nigra dopaminergic neurons

HL Wang, AH Chou, AS Wu, SY Chen, YH Weng… - … et Biophysica Acta (BBA …, 2011 - Elsevier
Mutations in PTEN-induced kinase 1 (PINK1) gene cause recessive familial type 6 of
Parkinson's disease (PARK6). PINK1 is believed to exert neuroprotective effect on SN …

Sensitivity and specificity of 99mTc-TRODAT-1 SPECT imaging in differentiating patients with idiopathic Parkinson's disease from healthy subjects

YH Weng, TC Yen, MC Chen, PF Kao… - Journal of Nuclear …, 2004 - Soc Nuclear Med
The imaging of dopamine transporter (DAT) with 99m Tc-TRODAT-1 ([2-[[2-[[[3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3,2,1]oct-2-yl]methyl](2-mercaptoethyl)amino]ethyl]amino]…

Correlation of Parkinson disease severity and 18F-DTBZ positron emission tomography

T Hsiao, YH Weng, CJ Hsieh, WY Lin, SP Wey… - JAMA …, 2014 - jamanetwork.com
Importance Currently, diagnosis of Parkinson disease is mainly based on clinical criteria
characterized by motor symptoms including bradykinesia, rigidity, resting tremor, and postural …

The effect of continuous theta burst stimulation over premotor cortex on circuits in primary motor cortex and spinal cord

…, JC Rothwell, CS Lu, JJ Wang, YH Weng… - Clinical …, 2009 - Elsevier
OBJECTIVE: To understand the effect of continuous theta burst stimulation (cTBS) given to
the premotor area, we studied the circuits within the primary motor cortex and spinal cord after …

HDAC inhibitor sodium butyrate reverses transcriptional downregulation and ameliorates ataxic symptoms in a transgenic mouse model of SCA3

AH Chou, SY Chen, TH Yeh, YH Weng… - Neurobiology of disease, 2011 - Elsevier
Spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant neurodegenerative disease
caused by polyglutamine-expanded ataxin-3. Previously, we prepared a SCA3 animal …

PLA2G6 mutations in PARK14‐linked young‐onset parkinsonism and sporadic Parkinson's disease

CS Lu, SC Lai, RM Wu, YH Weng… - American Journal of …, 2012 - Wiley Online Library
Mutations of PLA2G6 gene have been lately proposed to be the causative gene for PARK14
in patients with autosomal recessive young‐onset parkinsonism (YOPD). The role of …

[HTML][HTML] The add-on effect of Lactobacillus plantarum PS128 in patients with Parkinson's disease: a pilot study

CS Lu, HC Chang, YH Weng, CC Chen, YS Kuo… - Frontiers in …, 2021 - frontiersin.org
Background: Lactobacillus plantarum PS128 (PS128) is a specific probiotic, known as
psychobiotic, which has been demonstrated to alleviate motor deficits and inhibit …