User profiles for Yearn Seong Choe

Yearn Seong Choe

Samsung Medical Center, Sungkyunkwan University School of Medicine
Verified email at skku.edu
Cited by 6589

Safety and tumor tissue accumulation of pegylated graphene oxide nanosheets for co-delivery of anticancer drug and photosensitizer

W Miao, G Shim, S Lee, S Lee, YS Choe, YK Oh - Biomaterials, 2013 - Elsevier
Here, we report the safety, tumor accumulation and potential of polyethylene glycol-grafted
graphene oxide (pGO) as a multimodal nanocarrier of photosensitizers and synergistic …

Curcumin and Dehydrozingerone Derivatives:  Synthesis, Radiolabeling, and Evaluation for β-Amyloid Plaque Imaging

EK Ryu, YS Choe, KH Lee, Y Choi… - Journal of medicinal …, 2006 - ACS Publications
Alzheimer's disease (AD) is pathologically characterized by the accumulation of amyloid
plaques and neurofibrillary tangles in the brain, and thus, the in vivo imaging of plaques and …

Stereotactic brain injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimer's disease dementia: a phase 1 clinical trial

…, HJ Yun, JM Lee, ST Kim, YS Choe… - … Research & Clinical …, 2015 - Wiley Online Library
Introduction We conducted a phase 1 clinical trial in nine patients with mild‐to‐moderate
Alzheimer's disease to evaluate the safety and dose‐limiting toxicity of stereotactic brain …

Pathogenesis of cerebral microbleeds: in vivo imaging of amyloid and subcortical ischemic small vessel disease in 226 individuals with cognitive impairment

…, HJ Kim, CW Yoon, SJ Oh, JS Kim, YS Choe… - Annals of …, 2013 - Wiley Online Library
Objective Cerebral microbleeds (CMBs) are a neuroimaging marker of small vessel disease
(SVD) with relevance for understanding disease mechanisms in cerebrovascular disease, …

Cholesteryl hyaluronic acid-coated, reduced graphene oxide nanosheets for anti-cancer drug delivery

W Miao, G Shim, CM Kang, S Lee, YS Choe, HG Choi… - Biomaterials, 2013 - Elsevier
Here, we report hyaluronyl reduced graphene oxide (rGO) nanosheets as a tumor-targeting
delivery system for anticancer agents. Hyaluronyl-modified rGO nanosheets were prepared …

Synergistic effects of ischemia and β-amyloid burden on cognitive decline in patients with subcortical vascular mild cognitive impairment

…, BS Ye, J Chin, S Jeon, JM Lee, YS Choe… - JAMA …, 2014 - jamanetwork.com
Importance Cerebrovascular disease (CVD) and Alzheimer disease are significant causes
of cognitive impairment in the elderly. However, few studies have evaluated the relationship …

Gray and white matter changes linking cerebral small vessel disease to gait disturbances

…, J Lee, YK Jang, ST Kim, KH Lee, YS Choe… - Neurology, 2016 - AAN Enterprises
Objective: To investigate the topographic changes of white matter (WM) integrity and cortical
thickness related to gait disturbances and determine whether these neural correlates …

Amyloid burden, cerebrovascular disease, brain atrophy, and cognition in cognitively impaired patients

…, JM Lee, JK Seong, JS Kim, JH Lee, YS Choe… - Alzheimer's & …, 2015 - Elsevier
… Yoon f , Hee Jin Kim a , Juhee Chin a , Seun Jeon g , Jong Min Lee g , Joon-Kyung Seong
h , Jae Seung Kim i , Jae-Hong Lee j , Yearn Seong Choe k , Kyung Han Lee k , Young H. …

Clinical effect of white matter network disruption related to amyloid and small vessel disease

…, BS Ye, Y Noh, GH Kim, ED Ko, JS Kim, YS Choe… - Neurology, 2015 - AAN Enterprises
Background: We tested our hypothesis that the white matter network might mediate the effect
of amyloid and small vessel disease (SVD) on cortical thickness and/or cognition. Methods: …

Effects of cerebrovascular disease and amyloid beta burden on cognition in subjects with subcortical vascular cognitive impairment

…, ST Kim, S Jeon, JM Lee, SJ Oh, JS Kim, YS Choe… - Neurobiology of …, 2014 - Elsevier
Cerebrovascular disease (CVD) and amyloid burden are the most frequent pathologies in
subjects with cognitive impairment. However, the relationship between CVD, amyloid burden, …