A naturally occurred microtubullar silicate, halloysite nanotubes (HNTs), was co-cured with
epoxy/cyanate ester resin to form organic–inorganic hybrids. The coefficient of thermal …

The linker moiety of a proteolysis-targeting chimera (PROTAC) molecule plays a critical role
in modulating the degradation activity, target selectivity, and physico-chemical properties. …

A series of diaryl heterocyclic analogues were designed and synthesized as tubulin
polymerization inhibitors. Among them, compound 6y showed the highest antiproliferative activity …

Phosphodiesterase 4 (PDE4) hydrolyzes cyclic adenosine monophosphate (cAMP) and
plays a vital roles in many biological processes. PDE4 inhibitors have been widely studied as …

A mild, selective and redox-neutral Cp*Ir(III)- and Cp*Rh(III)-catalyzed C–H activation/annulation
of salicylaldehydes with fluorovinyl tosylates is reported. The use of monofluorovinyl …

A new reinforcing strategy for thermoplastics via hydrogen bonding bridged inorganics in the
matrix was proposed. The hydrogen bonds could be formed in thermoplastics matrices with …

This paper reports a practical and versatile oxidative cyclization of 2-arylethynylanilines
towards 2-hydroxy-2-substituted indol-3-ones via a copper-catalyzed radical approach in the …

α,α-Difluoromethyl carbinols are important structural motifs in many therapeutic agents and
functional materials. Herein, we developed a sustainable and efficient method for the …

Objective The purpose of the study is to investigate the performance of radiomics-based
analysis in prediction of pure ground-glass nodule (pGGN) lung adenocarcinomas invasiveness …

Selenium (Se), an essential micronutrient whose absence causes skeletal and cardiac
muscle dysfunction (Young, 1981; Sathe et al., 1992), is required for the proper function of the …