Therapeutic radiopharmaceuticals
WA Volkert, TJ Hoffman - Chemical reviews, 1999 - pubmed.ncbi.nlm.nih.gov
… WA Volkert …
[PDF][PDF] Technetium-99m d, l-HM-PAO: a new radiopharmaceutical for SPECT imaging of regional cerebral blood perfusion
…, RD Pickett, RA Holmes, WA Volkert… - Journal of Nuclear …, 1987 - Soc Nuclear Med
Following investigation of a large number of new ligands based upon propylene amine
oxime (PnAO) the d, l-diastereoisomer of hexamethyl propyleneamine oxime (HM-PAO) was …
oxime (PnAO) the d, l-diastereoisomer of hexamethyl propyleneamine oxime (HM-PAO) was …
Radiolabeled peptide conjugates for targeting of the bombesin receptor superfamily subtypes
CJ Smith, WA Volkert, TJ Hoffman - Nuclear medicine and biology, 2005 - Elsevier
Research laboratories around the world are currently focusing their efforts toward the
development of radiometallated, site-directed, diagnostic/therapeutic agents based upon small …
development of radiometallated, site-directed, diagnostic/therapeutic agents based upon small …
[PDF][PDF] Samarium-153-EDTMP: pharmacokinetic, toxicity and pain response using an escalating dose schedule in treatment of metastatic bone cancer
M Farhanghi, RA Holmes, WA Volkert… - Journal of Nuclear …, 1992 - Soc Nuclear Med
I452 The Journalof NuclearMedicine• Vol. 33 • No. 8 • August1992 more of the
following: x-ray,@ mTc@ HDPbone image, Cl'scan, MRI and bone biopsy. The study was …
following: x-ray,@ mTc@ HDPbone image, Cl'scan, MRI and bone biopsy. The study was …
Novel series of 111In-labeled bombesin analogs as potential radiopharmaceuticals for specific targeting of gastrin-releasing peptide receptors expressed on human …
…, DL Hayes, NK Owen, WA Volkert - Journal of Nuclear …, 2003 - Soc Nuclear Med
Gastrin-releasing peptide (GRP) receptors have been shown to be expressed with high
densities on several types of cancer cells including prostate, breast, small cell lung, and …
densities on several types of cancer cells including prostate, breast, small cell lung, and …
In vivo evaluation and small-animal PET/CT of a prostate cancer mouse model using 64Cu bombesin analogs: side-by-side comparison of the CB-TE2A and DOTA …
…, GL Sieckman, SD Figueroa, WA Volkert… - Journal of Nuclear …, 2007 - Soc Nuclear Med
The BB2 receptor subtype, of the bombesin family of receptors, has been shown to be highly
overexpressed in a variety of human tumors, including prostate cancer. Bombesin (BBN), a …
overexpressed in a variety of human tumors, including prostate cancer. Bombesin (BBN), a …
[PDF][PDF] Human pharmacokinetics of samarium-153 EDTMP in metastatic cancer
…, RA Holmes, M Farhangi, WA Volkert… - Journal of Nuclear …, 1989 - Soc Nuclear Med
METhOD Patient Selection Five patients with histopathologically proven primary can cer and
radiographic and/or scintigraphic bony metastases werestudiedunderphysiciansIND27865 (…
radiographic and/or scintigraphic bony metastases werestudiedunderphysiciansIND27865 (…
Radiochemical investigations of 177Lu-DOTA-8-Aoc-BBN [7-14] NH2: an in vitro/in vivo assessment of the targeting ability of this new radiopharmaceutical for PC-3 …
…, DL Hayes, NK Owen, DG Mazuru, WA Volkert… - Nuclear medicine and …, 2003 - Elsevier
Bombesin (BBN), a 14 amino acid peptide, is an analogue of human gastrin releasing peptide
(GRP) that binds to GRP receptors (GRPr) with high affinity and specificity. The GRPr is …
(GRP) that binds to GRP receptors (GRPr) with high affinity and specificity. The GRPr is …
A neutral lipophilic complex of 99mTc with a multidentate amine oxime
DE Troutner, WA Volkert, TJ Hoffman… - The International journal …, 1984 - Elsevier
Propylene amine oxime, 3,3′-(1,3-propanediyldiimino)bis(3-methyl-2-butanone)dioxine, (PnAO)
forms a neutral lipophilic complex with 99m Tc in > 95% yield at room temperature at …
forms a neutral lipophilic complex with 99m Tc in > 95% yield at room temperature at …
Radiochemical Investigations of Gastrin-releasing Peptide Receptor-specific [99mTc(X)(CO)3-Dpr-Ser-Ser-Ser-Gln-Trp-Ala-Val-Gly-His-Leu-Met-(NH2)] in PC-3, Tumor-bearing, Rodent Models: Syntheses, Radiolabeling, and …
…, DL Hayes, DG Mazuru, R Kannan, WA Volkert… - Cancer research, 2003 - AACR
Bombesin (BBN), a 14 amino acid peptide, is an analogue of human gastrin-releasing peptide
(GRP) that binds to GRP receptors (GRPrs) with high affinity and specificity. The GRPr is …
(GRP) that binds to GRP receptors (GRPrs) with high affinity and specificity. The GRPr is …