68Ga-labeled DOTA-peptides and 68Ga-labeled radiopharmaceuticals for positron emission tomography: current status of research, clinical applications, and future …
WAP Breeman, E De Blois, HS Chan… - Seminars in nuclear …, 2011 - Elsevier
In this review we give an overview of current knowledge of 68 Ga-labeled pharmaceuticals,
with focus on imaging receptor-mediated processes. A major advantage of a 68 Ge/ 68 Ga …
with focus on imaging receptor-mediated processes. A major advantage of a 68 Ge/ 68 Ga …
Radiolabelling DOTA-peptides with 68Ga
WAP Breeman, M de Jong, E de Blois… - European journal of …, 2005 - Springer
Purpose A new field of interest is the application of 68 Ga-labelled DOTA-conjugated
peptides for positron emission tomography (PET). The commercially available or house-made …
peptides for positron emission tomography (PET). The commercially available or house-made …
Optimising conditions for radiolabelling of DOTA-peptides with 90Y, 111In and 177Lu at high specific activities
WAP Breeman, M De Jong, TJ Visser, JL Erion… - European journal of …, 2003 - Springer
DOTA-conjugated peptides, such as [DOTA 0 ,Tyr 3 ]octreotide (DOTATOC) and [DOTA 0 ,Tyr
3 ]octreotate (DOTA-tate), can be labelled with radionuclides such as 90 Y, 111 In and 177 …
3 ]octreotate (DOTA-tate), can be labelled with radionuclides such as 90 Y, 111 In and 177 …
Simplified NaCl Based 68Ga Concentration and Labeling Procedure for Rapid Synthesis of 68Ga Radiopharmaceuticals in High Radiochemical Purity
…, M Gottschaldt, MK Schultz, WAP Breeman - Bioconjugate …, 2012 - ACS Publications
A simple sodium chloride (NaCl) based 68 Ga eluate concentration and labeling method that
enables rapid, high-efficiency labeling of DOTA conjugated peptides in high radiochemical …
enables rapid, high-efficiency labeling of DOTA conjugated peptides in high radiochemical …
[HTML][HTML] The 68Ge/68Ga generator has high potential, but when can we use 68Ga-labelled tracers in clinical routine?
WAP Breeman, AM Verbruggen - European journal of nuclear medicine …, 2007 - Springer
The 68Ge/68Ga generator has high potential, but when can we use 68Ga-labelled tracers
in clinical routine? | European Journal of Nuclear Medicine and Molecular Imaging Skip to …
in clinical routine? | European Journal of Nuclear Medicine and Molecular Imaging Skip to …
Effectiveness of quenchers to reduce radiolysis of 111In-or 177Lu-labelled methionine-containing regulatory peptides. Maintaining radiochemical purity as measured …
…, R de Zanger, W AP Breeman - Current Topics in …, 2012 - ingentaconnect.com
An overview how to measure and to quantify radiolysis by the addition of quenchers and to
maintain Radio- Chemical Purity (RCP) of vulnerable methionine-containing regulatory …
maintain Radio- Chemical Purity (RCP) of vulnerable methionine-containing regulatory …
Characteristics of SnO2-based 68Ge/68Ga generator and aspects of radiolabelling DOTA-peptides
…, D Prince, EP Krenning, WAP Breeman - Applied Radiation and …, 2011 - Elsevier
OBJECTIVES: PET scintigraphy with 68 Ga-labelled analogs is of increasing interest in
Nuclear Medicine and performed all over the world. Here we report the characteristics of the …
Nuclear Medicine and performed all over the world. Here we report the characteristics of the …
The untapped potential of Gallium 68-PET: The next wave of 68Ga-agents
DL Smith, WAP Breeman, J Sims-Mourtada - Applied Radiation and …, 2013 - Elsevier
68 Gallium-PET ( 68 Ga-PET) agents have significant clinical promise. The radionuclide can
be produced from a 68 Ge/ 68 Ga generator on site and is a convenient alternative to …
be produced from a 68 Ge/ 68 Ga generator on site and is a convenient alternative to …
Preclinical comparison of 111In-labeled DTPA-or DOTA-bombesin analogs for receptor-targeted scintigraphy and radionuclide therapy
WAP Breeman, M de Jong, JL Erion… - Journal of Nuclear …, 2002 - Soc Nuclear Med
The 14-amino-acid peptide bombesin (BN) has a high affinity for the gastrin-releasing peptide
(GRP) receptor that is expressed by a variety of tumors. Recently, high densities of GRP …
(GRP) receptor that is expressed by a variety of tumors. Recently, high densities of GRP …
Lanthanide (III) complexes of bis (phosphonate) monoamide analogues of DOTA: bone-seeking agents for imaging and therapy
…, ZI Kolar, HT Wolterbeek, WAP Breeman… - Journal of medicinal …, 2008 - ACS Publications
Lanthanide complexes of DOTA derivatives 2a (BPAMD) and 2b (BPAPD), having a monoamide
pendant arm with a bis(phosphonate) moiety, were comparatively tested for application …
pendant arm with a bis(phosphonate) moiety, were comparatively tested for application …