Evaluation of [18F]Fluoro-l-DOPA Positron Emission Tomography-Computed Tomography for Surgery in Focal Congenital Hyperinsulinism

…, H Mau, M Koch, C Hohne, W Mohnike… - The Journal of …, 2008 - academic.oup.com
Context: In congenital hyperinsulinism (CHI), the identification and precise localization of a
focal lesion is essential for successful surgery. Objective: Our objective was to evaluate the …

[HTML][HTML] Novel radiolabeled bisphosphonates for PET diagnosis and endoradiotherapy of bone metastases

…, M Bachmann, C Bal, M Sathekge, W Mohnike… - Pharmaceuticals, 2017 - mdpi.com
Bone metastases, often a consequence of breast, prostate, and lung carcinomas, are
characterized by an increased bone turnover, which can be visualized by positron emission …

Clinical and Genetic Evaluation of Patients with KATP Channel Mutations from the German Registry for Congenital Hyperinsulinism

K Mohnike, I Wieland, W Barthlen… - Hormone research in …, 2014 - karger.com
Congenital hyperinsulinism (CHI) causes hypoglycemia due to irregular insulin secretion. In
infants, a rapid diagnosis and appropriate management to avoid severe hypoglycemia is …

Patient‐related benefits of amyloid PET imaging in dementia: Rationale and design of the German randomized coverage with evidence development study ENABLE

…, R Buchert, W Mohnike, K Mohnike… - … Research & Clinical …, 2023 - Wiley Online Library
The utility of amyloid positron emission tomography (PET) for the etiological diagnosis of
dementia and its impact on functional status of patients in routine care are currently unclear. …

Techniques in pediatric surgery: congenital hyperinsulinism

W Barthlen, W Mohnike, K Mohnike - Hormone Research in Paediatrics, 2011 - karger.com
For surgery in congenital hyperinsulinism (CHI), a distinct surgical strategy and technique is
required for focal, diffuse and atypical CHI. In focal CHI, a confined, localized and …

Surgery in Focal Congenital Hyperinsulinism (CHI)-The" Hyperinsulinism Germany International" Experience in 30 Children.

…, W Mohnike, S Vogelgesang, K Mohnike - Pediatric …, 2016 - europepmc.org
Objectives Results of surgery for focal CHI in 30 children PATIENTS AND METHODS: All
showed an ABCC8 or KCNJ11 mutation. After PET/CT in 29 children and PET/MRT in 1 case, …

[BOOK][B] PET/CT-Atlas

W Mohnike, G Hör, H Schelbert - 2006 - Springer
Expertenkonsortien in USA und Europa sind sich einig in der Feststellung, dass die
Positronenemissionstomographie (PET) die rascheste Akzeptanz unter den bildgebenden …

Positron emission tomography/computed tomography diagnostics by means of fluorine-18-L-dihydroxyphenylalanine in congenital hyperinsulinism

W Mohnike, W Barthlen, K Mohnike… - Seminars in Pediatric …, 2011 - Elsevier
The unfavorable prognosis of congenital hyperinsulinism (CHI) can be avoided if the
patients are treated with high-dose glucose infusions and timely surgical intervention. …

Occurrence of giant focal forms of congenital hyperinsulinism with incorrect visualization by 18F DOPA‐PET/CT scanning

…, K Rothe, S Wächter, M Singer, W Mohnike… - Clinical …, 2014 - Wiley Online Library
Context Congenital hyperinsulinism ( CHI ) is a rare disease characterized by severe
hypoglycaemic episodes due to pathologically increased insulin secretion from the pancreatic beta …

Visualization of the focus in congenital hyperinsulinism by intraoperative sonography

…, K Mohnike, H Mau, T Eberhard, W Mohnike… - Seminars in Pediatric …, 2011 - Elsevier
In surgery for focal congenital hyperinsulinism (CHI), the identification and complete resection
of the focus without collateral damage is of utmost importance. In a pilot study we applied …