MR‐microscopic visualization of anisotropic internal cartilage structures using the magic angle technique

W Gründer, M Wagner, A Werner - Magnetic resonance in …, 1998 - Wiley Online Library
NMR microscopic studies of articular cartilage at 7.1 T are presented. Using a special
experimental design, T 2 ‐weighted spin‐echo images of cartilage‐bone plugs were taken under …

MRI assessment of cartilage ultrastructure

W Gründer - NMR in Biomedicine: An International Journal …, 2006 - Wiley Online Library
In T 2 ‐weighted MRI images joint cartilage can appear laminated. The multilaminar appearance
is visualized as zones of different intensity. This appearance is based on the dipolar …

Visualization of pressure distribution within loaded joint cartilage by application of angle‐sensitive NMR microscopy

W Gründer, M Kanowski, M Wagner… - Magnetic resonance in …, 2000 - Wiley Online Library
High‐resolution MRI measurements on knee joints show a multilaminar appearance of the
cartilage. This intracartilaginar structure, visualized as hypointense zones in T 2 ‐weighted …

Action of compression and cations on the proton and deuterium relaxation in cartilage

…, R Knauss, A Werner, W Gründer… - Magnetic resonance …, 1995 - Wiley Online Library
In this paper, investigations are described on the influence of osmotic pressures and of
varying cation concentrations on water relaxation times in cartilage (pig articular cartilage and …

Pulsed field gradient NMR and nuclear magnetic relaxation studies of water mobility in hydrated collagen II

R Knauss, G Fleischer, W Gründer… - Magnetic resonance …, 1996 - Wiley Online Library
Transverse nuclear magnetic relaxation and self‐diffusion of water were measured in hydrated
collagen II. Self‐diffusion measurements were conducted by pulsed field gradient NMR (…

The action of hypochlorous acid on polymeric components of cartilage

J Schiller, J Arnhold, W Gründer, K Arnold - 1994 - degruyter.com
Sodium hypochlorite causes a continuous decrease of the line for M-acetyl groups. Two
new resonances appear in the 1H-NMR spectra. An intermediate product, assumed as a …

Flexible add‐on solution for MR image‐guided interventions in a closed‐bore scanner environment

…, G Thörmer, D Zajonz, W Gründer… - Magnetic resonance …, 2010 - Wiley Online Library
MRI is of great clinical utility for the guidance of various diagnostic and therapeutic
procedures. In a standard closed‐bore scanner, the simplest approach is to manipulate the …

Method for automatic localization of MR‐visible markers using morphological image processing and conventional pulse sequences: Feasibility for image‐guided …

H Busse, R Trampel, W Gründer… - Journal of Magnetic …, 2007 - Wiley Online Library
Purpose To evaluate the feasibility and accuracy of an automated method to determine the
3D position of MR‐visible markers. Materials and Methods Inductively coupled RF coils were …

31P and 13C solid‐state NMR spectroscopy to study collagen synthesis and biomineralization in polymer‐based bone implants

F Weber, J Böhme, HA Scheidt, W Gründer… - NMR in …, 2012 - Wiley Online Library
A combination of solid‐state NMR spectroscopy and MRI was used to evaluate the formation
of extracellular matrix in poly(D,L‐lactide‐co‐glycolide) (PLGA) bone implants. Porous …

Calcium‐induced structural changes of cartilage proteoglycans studied by 1H NMR relaxometry and diffusion measurements

A Werner, W Gründer - … in Medicine: An Official Journal of the …, 1999 - Wiley Online Library
H transverse nuclear magnetic relaxation times (T 2 ) and self‐diffusion coefficients (SDCs)
of water were measured in isolated proteoglycan aggregates from pig articular cartilage. The …