Dynamic imaging of functionalized multi‐walled carbon nanotube systemic circulation and urinary excretion

…, D Emfietzoglou, S Mather, WT Phillips… - Advanced …, 2008 - Wiley Online Library
Intravenously administered, multi-walled carbon nanotubes functionalized with
diethylentriaminepentaacetic dianhydride (DTPA-MWNT) and radiolabeled with Indium-111 (111In), …

A simple method for producing a technetium-99m-labeled liposome which is stable in vivo

WT Phillips, AS Rudolph, B Goins, JH Timmons… - International journal of …, 1992 - Elsevier
… *All correspondence and reprint requests should be addressed to: Dr William T. Phillips,
Department of Radiology, The University of Texas Health Science Center, 7703 Floyd Curl Drive…

[PDF][PDF] Rapid gastric emptying of an oral glucose solution in type 2 diabetic patients

WT Phillips, JG Schwartz… - Journal of Nuclear …, 1992 - Soc Nuclear Med
RESULTS The gastric emptying pattern of the diabetic patients and the normal control subjects
are shown in Figure 1. The half-emptying time (Fig. 2) was significantly shorter (p= 0.0005…

Direct 99mTc labeling of pegylated liposomal doxorubicin (Doxil) for pharmacokinetic and non-invasive imaging studies

…, B Goins, R Klipper, G Negrete, WT Phillips - Journal of Pharmacology …, 2004 - ASPET
Pharmacokinetic and organ distribution studies of liposomal drugs in humans are a
challenge. A direct labeling method using 99m Tc-N,N-bis(2-mercaptoethyl)-N′,N′-diethyl-…

In vivo PET imaging and biodistribution of radiolabeled gold nanoshells in rats with tumor xenografts

H Xie, ZJ Wang, A Bao, B Goins, WT Phillips - International Journal of …, 2010 - Elsevier
Here we report the radiolabeling of gold nanoshells (NSs) for PET imaging in rat tumor
model. A conjugation method was developed to attach NSs with the radionuclide, 64 Cu. The …

[186Re] Liposomal doxorubicin (Doxil): in vitro stability, pharmacokinetics, imaging and biodistribution in a head and neck squamous cell carcinoma xenograft model

A Soundararajan, A Bao, WT Phillips, R Perez III… - Nuclear medicine and …, 2009 - Elsevier
The purpose of this study was to determine the feasibility of radiolabeling liposomal
doxorubicin (Doxil) for cancer chemoradionuclide therapy by directly loading the therapeutic …

Neutral and anionic liposome-encapsulated hemoglobin: effect of postinserted poly (ethylene glycol)-distearoylphosphatidylethanolamine on distribution and …

…, D Garcia, R Klipper, BA Goins, WT Phillips - … of Pharmacology and …, 2004 - ASPET
To prepare long-circulating liposomes, poly(ethylene glycol) (PEG)-lipid is usually mixed with
other lipid components before vesicle formation. PEG-lipids can also be postinserted in the …

Image-guided interventional therapy for cancer with radiotherapeutic nanoparticles

WT Phillips, A Bao, AJ Brenner, BA Goins - Advanced Drug Delivery …, 2014 - Elsevier
One of the major limitations of current cancer therapy is the inability to deliver tumoricidal
agents throughout the entire tumor mass using traditional intravenous administration. …

Rhenium-186 liposomes as convection-enhanced nanoparticle brachytherapy for treatment of glioblastoma

WT Phillips, B Goins, A Bao, D Vargas… - Neuro …, 2012 - academic.oup.com
Although external beam radiation is an essential component to the current standard treatment
of primary brain tumors, its application is limited by toxicity at doses more than80 Gy. …

The BEIR VII estimates of low-dose radiation health risks are based on faulty assumptions and data analyses: a call for reassessment

…, AH Maurer, AT Taylor, WT Phillips… - Journal of Nuclear …, 2018 - Soc Nuclear Med
The 2006 National Academy of Sciences Biologic Effects of Ionizing Radiation (BEIR) VII
report is a well-recognized and frequently cited source on the legitimacy of the linear no-…