PIK3CA as an oncogene in cervical cancer

…, J Whang-Peng, JM Liu, DM Yang, WK Yang… - Oncogene, 2000 - nature.com
Amplification of chromosome arm 3q is the most consistent aberration in cervical cancer, and
is implicated in the progression of dysplastic uterine cervical cells into invasive cancer. The …

Mesenchymal Stem Cell Targeting of Microscopic Tumors and Tumor Stroma Development Monitored by Noninvasive In vivo Positron Emission Tomography Imaging

SC Hung, WP Deng, WK Yang, RS Liu, CC Lee… - Clinical cancer …, 2005 - AACR
The aim of this study was to assess the efficacy human mesenchymal stem cells (hMSC) for
targeting microscopic tumors and suicide gene or cytokine gene therapy. Immunodeficient …

Tumor invasiveness and liver metastasis of colon cancer cells correlated with cyclooxygenase‐2 (COX‐2) expression and inhibited by a COX‐2–selective inhibitor …

…, JM Liu, M Hsiao, J Kou‐Lin, WK Yang - … journal of cancer, 2001 - Wiley Online Library
Non‐steroidal anti‐inflammatory drugs (NSAIDs) have been reported to reduce the risk and
mortality of colorectal cancer (CRC). Although the exact mechanisms remain unclear, the …

[HTML][HTML] COVID-19 will stimulate a new coronavirus research breakthrough: a 20-year bibliometric analysis

…, R Yao, K Wen, W Da, Y Meng, K Yang… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background COVID-19 is currently rampant in China, causing unpredictable harm to humans.
This study aimed to quantitatively and qualitatively investigate the research trends on …

Overexpression of cyclin A but not Skp 2 correlates with the tumor relapse of human hepatocellular carcinoma

Y Chao, YL Shih, JH Chiu, GY Chau, WY Lui, WK Yang… - Cancer research, 1998 - AACR
Cyclin A is an S- and G 2 -M-phase regulatory protein, and its abnormal expression has
been implicated in cellular transformation. This work was undertaken to investigate the …

S-and G2-phase cell cycle arrests and apoptosis induced by ganciclovir in murine melanoma cells transduced with herpes simplex virus thymidine kinase

SJ Wei, Y Chao, YM Hung, W Lin, DM Yang… - Experimental cell …, 1998 - Elsevier
Mechanism of cell killing by transfer of Herpes simplex virus type-1 thymidine kinase (HSVtk)
and subsequent ganciclovir (GCV) treatment was examined in B16F10 murine melanoma …

Synthesis and circularization of N-and B-tropic retroviral DNA Fv-1 permissive and restrictive mouse cells.

WK Yang, JO Kiggans, DM Yang… - Proceedings of the …, 1980 - National Acad Sciences
Production of various forms of nonintegrated viral DNA was measured in cultured mouse
cells carrying different Fv-1 alleles early after infection with N-tropic or B-tropic retroviruses. …

[HTML][HTML] Response of plant secondary metabolites to environmental factors

L Yang, KS Wen, X Ruan, YX Zhao, F Wei, Q Wang - Molecules, 2018 - mdpi.com
Plant secondary metabolites (SMs) are not only a useful array of natural products but also
an important part of plant defense system against pathogenic attacks and environmental …

Expression of elevated levels of pro‐inflammatory cytokines in SARS‐CoV‐infected ACE2+ cells in SARS patients: relation to the acute lung injury and pathogenesis …

…, L Yang, J Li, J Cai, L Qiu, K Wen… - The Journal of …, 2006 - Wiley Online Library
The authors have previously shown that acute lung injury (ALI) produces a wide spectrum of
pathological processes in patients who die of severe acute respiratory syndrome (SARS) …

[HTML][HTML] Comparative analysis of the transcriptome across distant species

…, KL Watkins, J Wen, K Wen, C Xue, L Yang, K Yip… - Nature, 2014 - nature.com
The transcriptome is the readout of the genome. Identifying common features in it across distant
species can reveal fundamental principles. To this end, the ENCODE and modENCODE …