[PDF][PDF] Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases
IDH1 and IDH2 mutations occur frequently in gliomas and acute myeloid leukemia, leading
to simultaneous loss and gain of activities in the production of α-ketoglutarate (α-KG) and 2-…
to simultaneous loss and gain of activities in the production of α-ketoglutarate (α-KG) and 2-…
The COVID-19 pandemic
M Ciotti, M Ciccozzi, A Terrinoni, WC Jiang… - Critical reviews in …, 2020 - Taylor & Francis
In December 2019, an outbreak of pneumonia of unknown origin was reported in Wuhan,
Hubei Province, China. Pneumonia cases were epidemiologically linked to the Huanan …
Hubei Province, China. Pneumonia cases were epidemiologically linked to the Huanan …
Nanoparticle-mediated cellular response is size-dependent
Nanostructures of different sizes, shapes and material properties have many applications in
biomedical imaging, clinical diagnostics and therapeutics 1 , 2 , 3 , 4 , 5 , 6 . In spite of what …
biomedical imaging, clinical diagnostics and therapeutics 1 , 2 , 3 , 4 , 5 , 6 . In spite of what …
EMAN2: an extensible image processing suite for electron microscopy
EMAN is a scientific image processing package with a particular focus on single particle
reconstruction from transmission electron microscopy (TEM) images. It was first released in 1999…
reconstruction from transmission electron microscopy (TEM) images. It was first released in 1999…
Understanding the High Activity of Fe–N–C Electrocatalysts in Oxygen Reduction: Fe/Fe3C Nanoparticles Boost the Activity of Fe–Nx
WJ Jiang, L Gu, L Li, Y Zhang, X Zhang… - Journal of the …, 2016 - ACS Publications
Understanding the origin of high activity of Fe–N–C electrocatalysts in oxygen reduction
reaction (ORR) is critical but still challenging for developing efficient sustainable nonprecious …
reaction (ORR) is critical but still challenging for developing efficient sustainable nonprecious …
[HTML][HTML] A novel therapy for colitis utilizing PPAR-γ ligands to inhibit the epithelial inflammatory response
CG Su, X Wen, ST Bailey, W Jiang… - The Journal of …, 1999 - Am Soc Clin Investig
Peroxisome proliferator-activated receptor γ (PPAR-γ), a member of the nuclear hormone
receptor superfamily originally shown to play a critical role in adipocyte differentiation and …
receptor superfamily originally shown to play a critical role in adipocyte differentiation and …
Hierarchical self-assembly of DNA into symmetric supramolecular polyhedra
DNA is renowned for its double helix structure and the base pairing that enables the recognition
and highly selective binding of complementary DNA strands. These features, and the …
and highly selective binding of complementary DNA strands. These features, and the …
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
…, TF Burns, ER McDonald 3rd, W Jiang… - Nature …, 1997 - pubmed.ncbi.nlm.nih.gov
… GS Wu, TF Burns, ER McDonald 3rd, W Jiang, R Meng, ID Krantz, G Kao, DD Gan, JY
Zhou, R Muschel, SR Hamilton, NB Spinner, S Markowitz, G Wu, WS el-Deiry …
Zhou, R Muschel, SR Hamilton, NB Spinner, S Markowitz, G Wu, WS el-Deiry …
[PDF][PDF] Proteogenomic characterization of pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor patient
survival. Toward understanding the underlying molecular alterations that drive PDAC …
survival. Toward understanding the underlying molecular alterations that drive PDAC …
TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain
DNA double-strand breaks enhance homologous recombination in cells and have been
exploited for targeted genome editing through use of engineered endonucleases. Here we …
exploited for targeted genome editing through use of engineered endonucleases. Here we …