The relationship between periodontal diseases and diabetes: an overview

WA Soskolne, A Klinger - Annals of periodontology, 2001 - Wiley Online Library
Diabetes mellitus, caused by the malfunction of insulin‐dependent glucose and lipid
metabolism, presents with the classical triad of symptoms: polydypsia, polyuria, and polyphagia …

Epidemiological and clinical aspects of periodontal diseases in diabetics

WA Soskolne - Annals of periodontology, 1998 - Wiley Online Library
The association between diabetes mellitus and periodontal disease has long been
discussed, with conflicting conclusions. On the one hand, numerous reports indicate a high …

Subgingival delivery of therapeutic agents in the treatment of periodontal diseases

WA Soskolne - Critical Reviews in Oral Biology & Medicine, 1997 - journals.sagepub.com
This article reviews the current status of controlled local delivery of antibacterial agents in the
treatment of periodontitis. The principle of local intrapocket delivery of antibacterial agents …

Sustained local delivery of chlorhexidine in the treatment of periodontitis: A multi‐center study

WA Soskolne, PA Heasman, A Stabholz… - Journal of …, 1997 - Wiley Online Library
The safety and efficacy of a degradable, subgingivally placed drag delivery system containing
2.5 mg Chlorhexidine (CHX) were evaluated in a randomized, blinded, multi‐center study …

Haim-Munk syndrome and Papillon-Lefevre syndrome are allelic mutations in cathepsin C

…, A Zlorogorski, L Shapira, WA Soskolne - Journal of medical …, 2000 - jmg.bmj.com
Of the many palmoplantar keratoderma (PPK) conditions, only Papillon-Lefèvre syndrome (PLS)
and Haim-Munk syndrome (HMS) are associated with premature periodontal destruction…

Protection against endotoxic shock and lipopolysaccharide-induced local inflammation by tetracycline: correlation with inhibition of cytokine secretion

L Shapira, WA Soskolne, Y Houri, V Barak… - Infection and …, 1996 - Am Soc Microbiol
Septic shock results from excessive stimulation of host immune cells, particularly monocytes
and macrophages, by lipopolysaccharide (LPS) released from gram-negative bacteria. …

The Secretion of PGE2, IL‐1β, IL‐6, and TNFα by Adherent Mononuclear Cells From Early Onset Periodontitis Patients

L Shapira, WA Soskolne, MN Sela… - Journal of …, 1994 - Wiley Online Library
… Stabholtz A, Soskolne V, Machtei E, Or R, Soskolne WA. Effect of benign familial …
Shapira L, Takashiba S, Kalmar JR, Van Dyke TE, Barak V, Soskolne WA. Rapid fluorometric …

An in vivo Study of the chlorhexidine release profile of the PerioChipTM in the gingival crevicular fluid, plasma and urine

WA Soskolne, T Chajek, M Flashner… - Journal of clinical …, 1998 - Wiley Online Library
The release profile of chlorhexidine from the PerioChip TM (Chip), a biodegradable local
delivery system that contains 2.5 mg of chlorhexidine gluconate (CHX) in a cross‐linked …

The effect of titanium surface roughness on the adhesion of monocytes and their secretion of TNF‐α and PGE2

WA Soskolne, S Cohen, L Shapira… - Clinical oral implants …, 2002 - Wiley Online Library
Dental implant surfaces are important in determining the tissue/surface interaction. One of
the first cells to adhere to the implant surface is the monocyte. This study examines the effect …

Periodontal destruction is associated with coronary artery disease and periodontal infection with acute coronary syndrome

I Gotsman, C Lotan, WA Soskolne… - Journal of …, 2007 - Wiley Online Library
Background: Coronary artery disease (CAD) is a highly prevalent disease with significant
morbidity and mortality. Periodontal disease has been suggested to influence this disease and …