Artificial-intelligence-based molecular classification of diffuse gliomas using rapid, label-free optical imaging

…, M Castro, LI Wadiura, G Widhalm, V Neuschmelting… - Nature medicine, 2023 - nature.com
Molecular classification has transformed the management of brain tumors by enabling more
accurate prognostication and personalized treatment. However, timely molecular diagnostic …

Mapping the hand, foot and face representations in the primary motor cortex—retest reliability of neuronavigated TMS versus functional MRI

C Weiss, C Nettekoven, AK Rehme, V Neuschmelting… - Neuroimage, 2013 - Elsevier
INTRODUCTION: Functional magnetic resonance imaging (fMRI) is a frequently used non-invasive
mapping technique for investigating the human motor system. Recently, …

Imaging of liver tumors using surface-enhanced Raman scattering nanoparticles

C Andreou, V Neuschmelting, DF Tschaharganeh… - ACS …, 2016 - ACS Publications
Complete surgical resection is the ideal first-line treatment for most liver malignancies. This
goal would be facilitated by an intraoperative imaging method that enables more precise …

[HTML][HTML] Performance of a multispectral optoacoustic tomography (MSOT) system equipped with 2D vs. 3D handheld probes for potential clinical translation

V Neuschmelting, NC Burton, H Lockau, A Urich… - Photoacoustics, 2016 - Elsevier
A handheld approach to optoacoustic imaging is essential for the clinical translation. The
first 2- and 3-dimensional handheld multispectral optoacoustic tomography (MSOT) probes …

Dual‐modality surface‐enhanced resonance Raman scattering and multispectral optoacoustic tomography nanoparticle approach for brain tumor delineation

V Neuschmelting, S Harmsen, N Beziere, H Lockau… - Small, 2018 - Wiley Online Library
Difficulty in visualizing glioma margins intraoperatively remains a major issue in the achievement
of gross total tumor resection and, thus, better clinical outcome of glioblastoma (GBM) …

Detection of premalignant gastrointestinal lesions using surface-enhanced resonance Raman scattering–nanoparticle endoscopy

…, S Rogalla, R Huang, M Spaliviero, V Neuschmelting… - Acs Nano, 2019 - ACS Publications
Cancers of the gastrointestinal (GI) tract are among the most frequent and most lethal
cancers worldwide. An important reason for this high mortality is that early disease is typically …

[HTML][HTML] Improved nTMS-and DTI-derived CST tractography through anatomical ROI seeding on anterior pontine level compared to internal capsule

C Weiss, I Tursunova, V Neuschmelting, H Lockau… - NeuroImage: Clinical, 2015 - Elsevier
Imaging of the course of the corticospinal tract (CST) by diffusion tensor imaging (DTI) is
useful for function-preserving tumour surgery. The integration of functional localizer data into …

Lymph node micrometastases and in-transit metastases from melanoma: in vivo detection with multispectral optoacoustic imaging in a mouse model

V Neuschmelting, H Lockau, V Ntziachristos, J Grimm… - Radiology, 2016 - pubs.rsna.org
Purpose To study whether multispectral optoacoustic tomography (MSOT) can serve as a
label-free imaging modality for the detection of lymph node micrometastases and in-transit …

[HTML][HTML] WST11 vascular targeted photodynamic therapy effect monitoring by multispectral optoacoustic tomography (MSOT) in mice

V Neuschmelting, K Kim, J Malekzadeh-Najafabadi… - Theranostics, 2018 - ncbi.nlm.nih.gov
Objective: Monitoring emerging vascular-targeted photodynamic therapy (VTP) and understanding
the time-dynamics of treatment effects remains challenging. We interrogated whether …

[HTML][HTML] Intraoperative microscopic autofluorescence detection and characterization in brain tumors using stimulated Raman histology and two-photon fluorescence

…, R Goldbrunner, O Bruns, V Neuschmelting - Frontiers in …, 2023 - frontiersin.org
The intrinsic autofluorescence of biological tissues interferes with the detection of fluorophores
administered for fluorescence guidance, an emerging auxiliary technique in oncological …