To identify susceptibility loci for bipolar disorder, we tested 1.8 million variants in 4,387 cases
and 6,209 controls and identified a region of strong association (rs10994336, P = 9.1 × 10 −…

Genes disrupted in schizophrenia may be revealed by de novo mutations in affected persons
from otherwise healthy families. Furthermore, during normal brain development, genes are …

Gene expression analyses of postmortem cerebral cortex suggest that transcription of the
regulator of G-protein signaling 4 ( RGS4 ) is decreased in a diagnosis-specific manner in …

A recent genome-wide association study (GWAS) reported evidence for association between
rs1344706 within ZNF804A (encoding zinc-finger protein 804A) and schizophrenia (P= …

Objective: Genetic factors contribute to the development of schizophrenia where cognitive
dysfunction is a hallmark. The purpose of this article was to examine computerized …

Several independent studies and meta-analyses aimed at identifying genomic regions linked
to bipolar disorder (BP) have failed to find clear and consistent evidence of linkage regions…

Abnormalities in circadian rhythms are prominent features of bipolar I disorder (BD1). To
investigate circadian variation in BD1, we evaluated morningness–eveningness (M/E), a stable …

Objective: Published studies suggest associations between circadian gene polymorphisms
and bipolar I disorder (BPI), as well as schizoaffective disorder (SZA) and schizophrenia (SZ)…

A number of reports of genetic association of human leucocyte antigens (HLA) and alleles
with schizophrenia have recently been published. A schizophrenia locus on chromosome 6p …

Diffusion tensor imaging (DTI) studies consistently reported abnormalities in fractional
anisotropy (FA) and radial diffusivity (RD), measures of the integrity of white matter (WM), in …