Canonical Wnt signaling requires inhibition of Glycogen Synthase Kinase 3 (GSK3) activity,
but the molecular mechanism by which this is achieved remains unclear. Here, we report …

Canonical Wnt signaling plays an important role in development and disease, regulating
transcription of target genes and stabilizing many proteins phosphorylated by glycogen …

Vertebrate Crossveinless-2 (CV2) is a secreted protein that can potentiate or antagonize
BMP signaling. Through embryological and biochemical experiments we find that: (1) CV2 …

Targeted diagnosis and therapy enable precise tumor detection and treatment. Successful
examples for precise tumor targeting are diagnostic and therapeutic radioligands. However, …

The present report describes the synthesis and biological evaluation of a molecular imaging
platform based on gold nanoparticles directly labeled with indium-111. The direct labeling …

… 1 C–F). One side of the dividing cell displayed strong diffuse cytoplasmic staining [see …
(F) Western blot analysis of hESCs treated with nocodazole; note that phosphorylated forms of …

The zinc finger/homeodomain transcription factor (zfhx1) family in vertebrates consists of two
members, δEF1 and SIP1. They have been proposed to display antagonistic activities in the …

The transmission of acquired immunodeficiency syndrome (AIDS) in tropical countries is
essentially heterosexual (PIOT et al., 1984). However, transmission by intramuscular injections …

… À f curves show an initial slow increase in hr with increase in f, but at a critical f value hr shows
a rapid increase with further increase in f. … above a high f value (40.6). The theoretical hr À …

… (B, D, and F) Results are expressed as the mean percentage of elongated caps per condition;
bars represent standard deviations. (G and H) Confocal micrographs of Xenopus animal …