User profiles for Victor Frenkel
 | Victor FrenkelAssociate Professor of Radiology, University of Maryland School of Medicine Verified email at som.umaryland.edu Cited by 5679 |
Ultrasound mediated delivery of drugs and genes to solid tumors
V Frenkel - Advanced drug delivery reviews, 2008 - Elsevier
It has long been shown that therapeutic ultrasound can be used effectively to ablate solid
tumors, and a variety of cancers are presently being treated in the clinic using these types of …
tumors, and a variety of cancers are presently being treated in the clinic using these types of …
Pulsed-high intensity focused ultrasound and low temperature–sensitive liposomes for enhanced targeted drug delivery and antitumor effect
S Dromi, V Frenkel, A Luk, B Traughber, M Angstadt… - Clinical cancer …, 2007 - AACR
Purpose: To determine if pulsed-high intensity focused ultrasound (HIFU) could effectively
serve as a source of hyperthermia with thermosensitive liposomes to enhance delivery and …
serve as a source of hyperthermia with thermosensitive liposomes to enhance delivery and …
Intramembrane cavitation as a unifying mechanism for ultrasound-induced bioeffects
The purpose of this study was to develop a unified model capable of explaining the
mechanisms of interaction of ultrasound and biological tissue at both the diagnostic nonthermal, …
mechanisms of interaction of ultrasound and biological tissue at both the diagnostic nonthermal, …
Image-guided drug delivery with magnetic resonance guided high intensity focused ultrasound and temperature sensitive liposomes in a rabbit Vx2 tumor model
…, CE Gacchina, KV Sharma, V Frenkel… - Journal of controlled …, 2012 - Elsevier
Clinical-grade doxorubicin encapsulated low temperature sensitive liposomes (LTSLs) were
combined with a clinical magnetic resonance-guided high intensity focused ultrasound (MR-…
combined with a clinical magnetic resonance-guided high intensity focused ultrasound (MR-…
Evolving drug delivery strategies to overcome the blood brain barrier
…, JG Perez, NP Connolly, V Frenkel… - Current …, 2016 - ingentaconnect.com
The blood-brain barrier (BBB) poses a unique challenge for drug delivery to the central
nervous system (CNS). The BBB consists of a continuous layer of specialized endothelial cells …
nervous system (CNS). The BBB consists of a continuous layer of specialized endothelial cells …
Visualizing normal and defective bone development in zebrafish embryos using the fluorescent chromophore calcein
Zebrafish have recently become a model of choice among developmental biologists. This
unique model enables both modern molecular and genetic studies to be carried out to identify …
unique model enables both modern molecular and genetic studies to be carried out to identify …
Large-scale juvenile production of the blue crab Callinectes sapidus
Rearing experiments and mass production of blue crab Callinectes sapidus juveniles were
carried out as the first step in a feasibility study of blue crab stock enhancement in the …
carried out as the first step in a feasibility study of blue crab stock enhancement in the …
Magnetic resonance imaging and confocal microscopy studies of magnetically labeled endothelial progenitor cells trafficking to sites of tumor angiogenesis
AC133 cells, a subpopulation of CD34 + hematopoietic stem cells, can transform into
endothelial cells that may integrate into the neovasculature of tumors or ischemic tissue. Most …
endothelial cells that may integrate into the neovasculature of tumors or ischemic tissue. Most …
Investigations into pulsed high-intensity focused ultrasound–enhanced delivery: preliminary evidence for a novel mechanism
Pulsed high-intensity focused ultrasound (HIFU) exposures without ultrasound contrast
agents have been used for noninvasively enhancing the delivery of various agents to improve …
agents have been used for noninvasively enhancing the delivery of various agents to improve …
Delivery of liposomal doxorubicin (Doxil) in a breast cancer tumor model: investigation of potential enhancement by pulsed-high intensity focused ultrasound exposure
V Frenkel, A Etherington, M Greene, J Quijano, J Xie… - Academic radiology, 2006 - Elsevier
RATIONALE AND OBJECTIVES: To investigate the potential of using pulsed high-intensity
focused ultrasound (HIFU) exposures to enhance the delivery, and hence therapeutic effect of …
focused ultrasound (HIFU) exposures to enhance the delivery, and hence therapeutic effect of …