User profiles for Vaishali Kapoor

vaishali kapoor

Washington University in St. Louis School of Medicine
Verified email at wustl.edu
Cited by 1042

Lactobacillus rhamnosus GG protects the intestinal epithelium from radiation injury through release of lipoteichoic acid, macrophage activation and the migration of …

…, D Alvarado, X Ee, A Zuckerman, L Foster, V Kapoor… - Gut, 2019 - gut.bmj.com
Objective Lactobacillus rhamnosus GG (LGG), a probiotic, given by gavage is radioprotective
of the mouse intestine. LGG-induced radioprotection is toll-like receptor 2 (TLR2) and …

[HTML][HTML] The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma

DYA Dadey, V Kapoor, A Khudanyan, F Urano… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Therapeutic resistance is a major barrier to improvement of outcomes for patients with
glioblastoma. The endoplasmic reticulum stress response (ERSR) has been identified as a …

Observing system simulation experiments at the National Centers for Environmental Prediction

…, S Greco, H Sun, J Terry, V Kapoor… - Journal of …, 2010 - Wiley Online Library
Observing system impact assessments using atmospheric simulation experiments are
conducted to provide an objective quantitative evaluation of future observing systems and …

[HTML][HTML] Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma

…, GP Sudlow, P de la Puente, B Muz, V Kapoor… - Nature …, 2020 - nature.com
Drug resistance and dose-limiting toxicities are significant barriers for treatment of multiple
myeloma (MM). Bone marrow microenvironment (BMME) plays a major role in drug …

6‐Gingerol mediates its anti tumor activities in human oral and cervical cancer cell lines through apoptosis and cell cycle arrest

V Kapoor, S Aggarwal, SN Das - Phytotherapy research, 2016 - Wiley Online Library
6‐Gingerol, a potent nutraceutical, has been shown to have antitumor activity in different
tumors, although its mechanism of action is not well understood. In this study, we evaluated …

Long-acting recombinant human interleukin-7, NT-I7, increases cytotoxic CD8 T cells and enhances survival in mouse glioma models

JL Campian, S Ghosh, V Kapoor, R Yan, S Thotala… - Clinical Cancer …, 2022 - AACR
Purpose: Patients with glioblastoma (GBM) are treated with radiotherapy (RT) and temozolomide
(TMZ). These treatments may cause prolonged systemic lymphopenia, which itself is …

Antibody targeting GRP78 enhances the efficacy of radiation therapy in human glioblastoma and non–small cell lung cancer cell lines and tumor models

DYA Dadey, V Kapoor, K Hoye, A Khudanyan… - Clinical Cancer …, 2017 - AACR
Purpose: Non–small cell lung cancer (NSCLC) and glioblastoma multiforme (GBM) have
poor median survival. NSCLC and GBM overexpress glucose regulated protein 78 (GRP78), …

Erufosine simultaneously induces apoptosis and autophagy by modulating the Akt–mTOR signaling pathway in oral squamous cell carcinoma

V Kapoor, MM Zaharieva, SN Das, MR Berger - Cancer letters, 2012 - Elsevier
We investigated the anticancer activity of erufosine in oral squamous carcinoma cell lines in
terms of cell proliferation, colony formation, induction of autophagy/apoptosis, cell cycle and …

PERK regulates glioblastoma sensitivity to ER stress although promoting radiation resistance

DYA Dadey, V Kapoor, A Khudanyan, D Thotala… - Molecular Cancer …, 2018 - AACR
The aggressive nature and inherent therapeutic resistance of glioblastoma multiforme (GBM)
has rendered the median survival of afflicted patients to 14 months. Therefore, it is …

[HTML][HTML] Role of midkine in cancer drug resistance: regulators of its expression and its molecular targeting

M Saikia, N Cheung, AK Singh, V Kapoor - International journal of …, 2023 - mdpi.com
Molecules involved in drug resistance can be targeted for better therapeutic efficacies.
Research on midkine (MDK) has escalated in the last few decades, which affirms a positive …