68Ga-Complex Lipophilicity and the Targeting Property of a Urea-Based PSMA Inhibitor for PET Imaging

M Eder, M Schäfer, U Bauder-Wüst… - Bioconjugate …, 2012 - ACS Publications
Urea-based inhibitors of the prostate-specific membrane antigen (PSMA) represent low-molecular-weight
pepidomimetics showing the ability to image PSMA-expressing prostate tumors…

Preclinical evaluation of a tailor-made DOTA-conjugated PSMA inhibitor with optimized linker moiety for imaging and endoradiotherapy of prostate cancer

M Benešová, M Schäfer, U Bauder-Wüst… - Journal of Nuclear …, 2015 - Soc Nuclear Med
Despite many advances in the past years, the treatment of metastatic prostate cancer still
remains challenging. In recent years, prostate-specific membrane antigen (PSMA) inhibitors …

[HTML][HTML] Novel Preclinical and Radiopharmaceutical Aspects of [68Ga]Ga-PSMA-HBED-CC: A New PET Tracer for Imaging of Prostate Cancer

M Eder, O Neels, M Müller, U Bauder-Wüst, Y Remde… - Pharmaceuticals, 2014 - mdpi.com
Ulrike Bauder-Wüst contributed in the data interpretation and analysis and carried out in
vitro experiments. Yvonne Remde contributed to the development of the GMP-compliant …

Preclinical evaluation of 18F-PSMA-1007, a new prostate-specific membrane antigen ligand for prostate cancer imaging

…, M Schäfer, M Benešová, U Bauder-Wüst… - Journal of Nuclear …, 2017 - Soc Nuclear Med
In recent years, several radiotracers targeting the prostate-specific membrane antigen (PSMA)
have been introduced. Some of them have had a high clinical impact on the treatment of …

[HTML][HTML] A dimerized urea-based inhibitor of the prostate-specific membrane antigen for 68Ga-PET imaging of prostate cancer

M Schäfer, U Bauder-Wüst, K Leotta, F Zoller, W Mier… - EJNMMI research, 2012 - Springer
Background Alternative positron-emission tomography (PET) probes like labeled inhibitors
of the prostate-specific membrane antigen (PSMA) are of emerging clinical impact as they …

Linker modification strategies to control the prostate-specific membrane antigen (PSMA)-targeting and pharmacokinetic properties of DOTA-conjugated PSMA …

M Benesova, U Bauder-Wüst… - Journal of Medicinal …, 2016 - ACS Publications
Since prostate-specific membrane antigen (PSMA) is up-regulated in nearly all stages of
prostate cancer (PCa), PSMA can be considered as a viable diagnostic biomarker and …

Preclinical evaluation of a bispecific low‐molecular heterodimer targeting both PSMA and GRPR for improved PET imaging and therapy of prostate cancer

M Eder, M Schäfer, U BauderWüst, U Haberkorn… - The …, 2014 - Wiley Online Library
BACKGROUND It has recently been reported that metastases of prostate cancer usually
show highly heterogeneous or partly lost prostate‐specific membrane antigen (PSMA) …

PSMA-11–derived dual-labeled PSMA inhibitors for preoperative PET imaging and precise fluorescence-guided surgery of prostate cancer

AC Baranski, M Schäfer, U Bauder-Wüst… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Resection of tumors using targeted dual-modality probes combining preoperative imaging
with intraoperative guidance is of high clinical relevance and might considerably affect the …

[HTML][HTML] Development and dosimetry of 203Pb/212Pb-labelled PSMA ligands: bringing “the lead” into PSMA-targeted alpha therapy?

JC Dos Santos, M Schäfer, U Bauder-Wüst… - European Journal of …, 2019 - Springer
Purpose The aims of this study were to develop a prostate-specific membrane antigen (PSMA)
ligand for labelling with different radioisotopes of lead and to obtain an approximation of …

[HTML][HTML] Design of internalizing PSMA-specific Glu-ureido-based radiotherapeuticals

T Wüstemann, U Bauder-Wüst, M Schäfer, M Eder… - Theranostics, 2016 - ncbi.nlm.nih.gov
Ulrike Bauder-Wüst contributed in collaborating in carrying out the in vitro experiments and
in the data interpretation and analysis of these. Martin Schäfer contributed to the syntheses of …