German multicenter study investigating 177Lu-PSMA-617 radioligand therapy in advanced prostate cancer patients

…, A Pfestroff, M Luster, U Lützen… - Journal of Nuclear …, 2017 - Soc Nuclear Med
177 Lu-labeled PSMA-617 is a promising new therapeutic agent for radioligand therapy (RLT)
of patients with metastatic castration-resistant prostate cancer (mCRPC). Initiated by the …

Man as living bioreactor: fate of an exogenously prepared customized tissue-engineered mandible

…, H Bolte, M Kosmahl, PAJ Russo, E Sherry, U Lützen… - Biomaterials, 2006 - Elsevier
In 2004, we reported a novel method of repairing a human mandible by in vivo tissue
engineering. The patient served as his own bioreactor as the exogenously prepared customized …

Cutting edge: immunological consequences and trafficking of human regulatory macrophages administered to renal transplant recipients

…, HH Oberg, A Pascher, U Lützen… - The Journal of …, 2011 - journals.aai.org
Regulatory macrophages (M regs) were administered to two living-donor renal transplant
recipients. Both patients were minimized to low-dose tacrolimus monotherapy within 24 wk of …

Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease

…, A Arlt, D Kabelitz, M Ellrichmann, U Lützen… - Gut, 2019 - gut.bmj.com
Objective Vedolizumab, a monoclonal antibody directed against the integrin heterodimer
α4β7, is approved for the treatment of Crohn’s disease and ulcerative colitis. The efficacy of …

Pulmonary functional imaging: qualitative comparison of Fourier decomposition MR imaging with SPECT/CT in porcine lung

G Bauman, U Lützen, M Ullrich, T Gaass, J Dinkel… - Radiology, 2011 - pubs.rsna.org
Purpose To compare unenhanced lung ventilation-weighted (VW) and perfusion-weighted (QW)
imaging based on Fourier decomposition (FD) magnetic resonance (MR) imaging with …

Man as a living bioreactor: prefabrication of a custom vascularized bone graft in the gastrocolic omentum

J Wiltfang, M Rohnen, JH Egberts, U Lützen… - … Engineering Part C …, 2016 - liebertpub.com
Reconstruction of critical-size jaw defects still remains challenging. The standard treatment
today is transplantation of autologous bone grafts, which is associated with high donor-site …

[HTML][HTML] Neuroprotective and antioxidative effects of pioglitazone in brain tissue adjacent to the ischemic core are mediated by PI3K/Akt and Nrf2/ARE pathways

Y Zhao, U Lützen, P Gohlke, P Jiang… - Journal of Molecular …, 2021 - Springer
The present study elucidates the neuroprotective mechanisms of the PPARγ (peroxisome
proliferator-activated receptor γ) agonist pioglitazone in survival of ischemic neurons following …

[HTML][HTML] Automated synthesis of [68Ga]Ga-FAPI-46 without pre-purification of the generator eluate on three common synthesis modules and two generator types

A Alfteimi, U Lützen, A Helm, M Jüptner, M Marx… - EJNMMI radiopharmacy …, 2022 - Springer
Background The recent development of quinoline-based radiotracers, which act as
fibroblast activation protein inhibitors (FAPIs), has shown promising preclinical and clinical …

[HTML][HTML] Case report: arterial wall inflammation in atherosclerotic cardiovascular disease is reduced by olamkicept (sgp130Fc)

…, M Laudes, S Rose-John, U Lützen… - Frontiers in …, 2022 - frontiersin.org
Inflammation is a strong driver of atherosclerotic cardiovascular disease (ASCVD). There is
a large unmet need for therapies that prevent or reduce excessive inflammation while …

Evaluation of the diagnostic value of preoperative sentinel lymph node (SLN) imaging in penile carcinoma patients without palpable inguinal lymph nodes via single …

…, KP Jünemann, M Zuhayra, U Lützen - … Oncology: Seminars and …, 2018 - Elsevier
Background Sentinel lymph node (SLN) biopsy represents a well-established diagnostic tool
for the assessment of lymphatic metastasis. Correct pre- and intraoperative visualization of …