[HTML][HTML] Recent developments on PET radiotracers for TSPO and their applications in neuroimaging

L Zhang, K Hu, T Shao, L Hou, S Zhang, W Ye… - … Pharmaceutica Sinica B, 2021 - Elsevier
The 18 kDa translocator protein (TSPO), previously known as the peripheral benzodiazepine
receptor, is predominately localized to the outer mitochondrial membrane in steroidogenic …

Hepatic transferrin plays a role in systemic iron homeostasis and liver ferroptosis

…, L Duan, S Wang, K Wang, P An, T Shao… - Blood, The Journal …, 2020 - ashpublications.org
Although the serum-abundant metal-binding protein transferrin (encoded by the Trf gene) is
synthesized primarily in the liver, its function in the liver is largely unknown. Here, we …

[HTML][HTML] Probiotic Lactobacillus rhamnosus GG prevents liver fibrosis through inhibiting hepatic bile acid synthesis and enhancing bile acid excretion in mice

Y Liu, K Chen, F Li, Z Gu, Q Liu, L He, T Shao… - Hepatology, 2020 - journals.lww.com
The Tumor Suppressor Interferon Regulatory Factor 2 Binding... : Hepatology The Tumor
Suppressor Interferon Regulatory Factor 2 Binding Protein 2 Regulates Hippo Pathway in Liver …

Intestinal HIF-1α deletion exacerbates alcoholic liver disease by inducing intestinal dysbiosis and barrier dysfunction

T Shao, C Zhao, F Li, Z Gu, L Liu, L Zhang, Y Wang… - Journal of …, 2018 - Elsevier
Background & Aims Alcoholic liver disease (ALD) is characterized by gut dysbiosis and
increased gut permeability. Hypoxia inducible factor 1α (HIF-1α) has been implicated in …

Ferulic acid increases pain threshold and ameliorates depression-like behaviors in reserpine-treated mice: behavioral and neurobiological analyses

Y Xu, L Zhang, T Shao, L Ruan, L Wang, J Sun… - Metabolic brain …, 2013 - Springer
Depression-pain dyad involves a series of pathological changes including the dysfunction of
neuroendocrine and immune networks. Depression and pain influence each other, but the …

[HTML][HTML] Differentially expressed immune response genes in COVID-19 patients based on disease severity

…, Y Li, M Li, Y Gao, T Li, S Li, L Tan, T Shao… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Background: Dysregulated immune responses to severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) are thought to underlie the progression of coronavirus disease 2019 (…

[HTML][HTML] Fatty acids activate the transcriptional coactivator YAP1 to promote liver fibrosis via p38 mitogen-activated protein kinase

…, AJ Jeyarajan, AJ Kruger, JA Holmes, T Shao… - Cellular and Molecular …, 2021 - Elsevier
Background & Aims Patients with simple steatosis (SS) and nonalcoholic steatohepatitis
can develop progressive liver fibrosis, which is associated with liver-related mortality. The …

Imaging Leucine-Rich Repeat Kinase 2 In Vivo with 18F-Labeled Positron Emission Tomography Ligand

…, L Chen, CH Yoo, J Rong, H Fu, T Shao… - Journal of Medicinal …, 2022 - ACS Publications
Leucine-rich repeat kinase 2 (LRRK2) has been demonstrated to be closely involved in the
pathogenesis of Parkinson’s disease (PD), and pharmacological blockade of LRRK2 …

Probiotic culture supernatant improves metabolic function through FGF21-adiponectin pathway in mice

QI Liu, Y Liu, F Li, Z Gu, M Liu, T Shao, L Zhang… - The Journal of nutritional …, 2020 - Elsevier
… Author links open overlay panel Qi Liu a c d e , Yunhuan Liu c d e , Fengyuan Li d e f ,
Zelin Gu c d e , Min Liu b c d e , Tuo Shao c d e , Lihua Zhang c d e , Guangyao Zhou a c d e , …

Circular RNA LARP4 correlates with decreased Enneking stage, better histological response, and prolonged survival profiles, and it elevates chemosensitivity to …

Y Hu, J Gu, H Shen, T Shao, S Li… - Journal of Clinical …, 2020 - Wiley Online Library
Background This study aimed to evaluate the association of circular RNA La‐related RNA‐binding
protein 4 (circ‐LARP4) with clinical features and prognosis in osteosarcoma patients, …