Multimodal Image-Guided Photothermal Therapy Mediated by 188Re-Labeled Micelles Containing a Cyanine-Type Photosensitizer

CL Peng, YH Shih, PC Lee, TMH Hsieh, TY Luo… - ACS …, 2011 - ACS Publications
Multifunctional micelles loaded with the near-infrared (NIR) dye and labeled with the
radionuclide rhenium-188 ( 188 Re) have been developed to provide multimodalities for NIR …

Targeting colorectal cancer stem-like cells with anti-CD133 antibody-conjugated SN-38 nanoparticles

…, PC Lee, YH Shih, CY Lin, TY Luo… - … applied materials & …, 2016 - ACS Publications
Cancer stem-like cells play a key role in tumor development, and these cells are relevant to
the failure of conventional chemotherapy. To achieve favorable therapy for colorectal cancer, …

[HTML][HTML] Neutrophil elastase as a diagnostic marker and therapeutic target in colorectal cancers

…, CH Chen, CC Cheng, CC Wang, HC Lin, TY Luo… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Neutrophil elastase (NE), a serine protease secreted by neutrophils, contributes to the
progression of cancers to enhance tumor invasion and metastasis. It has been well reported that …

Development of pH sensitive 2-(diisopropylamino) ethyl methacrylate based nanoparticles for photodynamic therapy

CL Peng, LY Yang, TY Luo, PS Lai, SJ Yang… - …, 2010 - iopscience.iop.org
Photodynamic therapy is an effective treatment for tumors that involves the administration of
light-activated photosensitizers. However, most photosensitizers are insoluble and non-…

Biodistribution, pharmacokinetics and microSPECT/CT imaging of 188Re-bMEDA-liposome in a C26 murine colon carcinoma solid tumor animal model

…, TJ Chang, CY Yu, LC Chen, ML Jan, TY Luo… - Anticancer …, 2007 - ar.iiarjournals.org
Nanoliposomes are useful carriers in drug delivery. Radiolabeled nanoliposomes have
potential applications in radiotherapy and diagnostic imaging. In this study, the biodistribution …

[HTML][HTML] Blocking heme oxygenase-1 by zinc protoporphyrin reduces tumor hypoxia-mediated VEGF release and inhibits tumor angiogenesis as a potential …

…, SS Guan, HJ Yang, CC Chang, TY Luo… - Journal of biomedical …, 2016 - Springer
Background Hypoxia in tumor niche is one of important factors to start regeneration of blood
vessels, leading to increase survival, proliferation, and invasion in cancer cells. Under …

Characterization of neuroblastic tumors using 18F-FDOPA PET

…, DT Lin, YL Lee, H Lee, PY Wu, TY Luo… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Neuroblastic tumors are childhood neoplasms that possess amino acid decarboxylase (AADC)
activity and can theoretically be imaged by 18 F-fluorodihydroxyphenylalanine ( 18 F-…

EGFR-targeted micelles containing near-infrared dye for enhanced photothermal therapy in colorectal cancer

YH Shih, TY Luo, PF Chiang, CJ Yao, WJ Lin… - Journal of Controlled …, 2017 - Elsevier
The purpose of this research was to investigate the effectiveness of epidermal growth factor
receptor (EGFR) targeted micelles loaded with IR-780 (Cetuximab/IR-780/micelles) for …

Biodistribution, pharmacokinetics and imaging of 188Re-BMEDA-labeled pegylated liposomes after intraperitoneal injection in a C26 colon carcinoma ascites mouse …

…, YJ Chang, WC Hsu, CL Ho, CH Yeh, TY Luo… - Nuclear medicine and …, 2007 - Elsevier
Nanoliposomes are important carriers capable of packaging drugs for various delivery
applications through passive targeting tumor sites by enhanced permeability and retention effect. …

Development of thermosensitive poly (n-isopropylacrylamide-co-((2-dimethylamino) ethyl methacrylate))-based nanoparticles for controlled drug release

CL Peng, HM Tsai, SJ Yang, TY Luo, CF Lin… - …, 2011 - iopscience.iop.org
Thermosensitive nanoparticles based on poly (N-isopropylacrylamide-co-((2-dimethylamino)
ethylmethacrylate))(poly (NIPA-co-DMAEMA)) copolymers were successfully fabricated by …