In Vivo Imaging of Prostate Cancer Using [68Ga]-Labeled Bombesin Analog BAY86-7548
…, I Jambor, J Kemppainen, K Lehtiö, TJ Grönroos… - Clinical cancer …, 2013 - AACR
Purpose: A novel [ 68 Ga]-labeled DOTA-4-amino-1-carboxymethyl-piperidine-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH
2 peptide (BAY86-7548) having high affinity to bombesin …
2 peptide (BAY86-7548) having high affinity to bombesin …
18F-EF5: a new PET tracer for imaging hypoxia in head and neck cancer
…, O Eskola, P Lindholm, TJ Grönroos… - Journal of nuclear …, 2008 - Soc Nuclear Med
The aim of this study was to evaluate 2-(2-nitro- 1 H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)-acetamide
(EF5) labeled with 18 F-fluorine to image hypoxia in patients with …
(EF5) labeled with 18 F-fluorine to image hypoxia in patients with …
Hypo-and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms
…, S Jin, M Busk, R Borra, TJ Grönroos… - Proceedings of the …, 2011 - National Acad Sciences
A switch from oxidative phosphorylation to glycolysis is frequently observed in cancer cells
and is linked to tumor growth and invasion, but the underpinning molecular mechanisms …
and is linked to tumor growth and invasion, but the underpinning molecular mechanisms …
[HTML][HTML] More than meets the eye: scientific rationale behind molecular imaging and therapeutic targeting of prostate-specific membrane antigen (PSMA) in metastatic …
A Hyväkkä, V Virtanen, J Kemppainen, TJ Grönroos… - Cancers, 2021 - mdpi.com
Simple Summary Prostate-specific membrane antigen (PSMA) is a transmembrane protein
that is overexpressed in prostate cancer and correlates with the aggressiveness of the …
that is overexpressed in prostate cancer and correlates with the aggressiveness of the …
CIP2A interacts with TopBP1 and drives basal-like breast cancer tumorigenesis
…, AN Cvrljevic, JP Vainonen, FM Feringa, TJ Grönroos… - Cancer research, 2021 - AACR
These results identify CIP2A as a nongenetic driver and therapeutic target in basal-like breast
cancer that regulates DNA damage–induced G 2 –M checkpoint and proliferative signaling…
cancer that regulates DNA damage–induced G 2 –M checkpoint and proliferative signaling…
[HTML][HTML] Hypoxia, blood flow and metabolism in squamous-cell carcinoma of the head and neck: correlations between multiple immunohistochemical parameters and …
TJ Grönroos, K Lehtiö, KO Söderström, P Kronqvist… - Bmc Cancer, 2014 - Springer
Background The relationship between the uptake of [ 18 F]fluoroerythronitroimidazole ([ 18 F]FETNIM),
blood flow ([ 15 O]H 2 O) and 2-[ 18 F]fluoro-2-deoxyglucose ([ 18 F]FDG) and …
blood flow ([ 15 O]H 2 O) and 2-[ 18 F]fluoro-2-deoxyglucose ([ 18 F]FDG) and …
[HTML][HTML] Repeatability of tumour hypoxia imaging using [18F]EF5 PET/CT in head and neck cancer
…, V Saunavaara, O Solin, TJ Grönroos… - European Journal of …, 2018 - Springer
Purpose Hypoxia contributes to radiotherapy resistance and more aggressive behaviour of
several types of cancer. This study was designed to evaluate the repeatability of intratumour …
several types of cancer. This study was designed to evaluate the repeatability of intratumour …
[HTML][HTML] Intravenous transplantation of olfactory ensheathing cells reduces neuroinflammation after spinal cord injury via interleukin-1 receptor antagonist
…, O Solin, S Forsback, TJ Grönroos… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: Olfactory ensheathing cell (OEC) transplantation has emerged as a promising
therapy for spinal cord injury (SCI) repair. In the present study, we explored the possible …
therapy for spinal cord injury (SCI) repair. In the present study, we explored the possible …
[HTML][HTML] Targeted deletion of keratin 8 in intestinal epithelial cells disrupts tissue integrity and predisposes to tumorigenesis in the colon
CGA Stenvall, M Tayyab, TJ Grönroos… - Cellular and Molecular …, 2022 - Springer
Keratin 8 (K8) is the main intestinal epithelial intermediate filament protein with proposed
roles for colonic epithelial cell integrity. Here, we used mice lacking K8 in intestinal epithelial …
roles for colonic epithelial cell integrity. Here, we used mice lacking K8 in intestinal epithelial …
Measurement of brown adipose tissue mass using a novel dual-echo magnetic resonance imaging approach: a validation study
…, TJ Grönroos, J Laine, V Lepomäki, J Saunavaara… - Metabolism, 2013 - Elsevier
Objective The aim of this study was to evaluate and validate magnetic resonance imaging (MRI)
for the visualization and quantification of brown adipose tissue (BAT) in vivo in a rat …
for the visualization and quantification of brown adipose tissue (BAT) in vivo in a rat …