Definitions and diagnosis of pulmonary hypertension

…, M Kurzyna, D Langleben, A Manes, T Satoh… - Journal of the American …, 2013 - jacc.org
Pulmonary hypertension (PH) is defined by a mean pulmonary artery pressure ≥25 mm Hg
at rest, measured during right heart catheterization. There is still insufficient evidence to add …

Diagnosis of pulmonary hypertension

…, D Khanna, A Manes, R Oudiz, T Satoh… - European …, 2019 - Eur Respiratory Soc
A revised diagnostic algorithm provides guidelines for the diagnosis of patients with
suspected pulmonary hypertension, both prior to and following referral to expert centres, and …

Treatment of pulmonary hypertension

…, VV McLaughlin, AM Al Dalaan, T Satoh… - The Lancet …, 2016 - thelancet.com
The most common forms of pulmonary hypertension are pulmonary arterial hypertension,
chronic thromboembolic pulmonary hypertension, and pulmonary hypertension due to left-…

Clinical correlates and prognostic significance of six-minute walk test in patients with primary pulmonary hypertension: comparison with cardiopulmonary exercise …

S Miyamoto, N Nagaya, T Satoh, S Kyotani… - American journal of …, 2000 - atsjournals.org
The six-minute walk test is a submaximal exercise test that can be performed even by a
patient with heart failure not tolerating maximal exercise testing. To elucidate the clinical …

Plasma brain natriuretic peptide as a prognostic indicator in patients with primary pulmonary hypertension

N Nagaya, T Nishikimi, M Uematsu, T Satoh… - Circulation, 2000 - Am Heart Assoc
Background—Plasma brain natriuretic peptide (BNP) level increases in proportion to the
degree of right ventricular dysfunction in pulmonary hypertension. We sought to assess the …

Plasma brain natriuretic peptide levels increase in proportion to the extent of right ventricular dysfunction in pulmonary hypertension

…, T Nishikimi, Y Okano, M Uematsu, T Satoh… - Journal of the American …, 1998 - jacc.org
Objectives. This study sought to investigate the influence of right ventricular (RV) hemodynamic
variables and function on the secretion of brain natriuretic peptide (BNP) in patients with …

Imatinib mesylate as add-on therapy for pulmonary arterial hypertension: results of the randomized IMPRES study

…, PM Hassoun, NW Morrell, AJ Peacock, T Satoh… - Circulation, 2013 - Am Heart Assoc
Background— By its inhibitory effect on platelet-derived growth factor signaling, imatinib
could be efficacious in treating patients with pulmonary arterial hypertension (PAH). Methods …

Percutaneous transluminal pulmonary angioplasty for the treatment of chronic thromboembolic pulmonary hypertension

…, M Ando, K Fukuda, H Yoshino, T Satoh - Circulation …, 2012 - Am Heart Assoc
Background— Chronic thromboembolic pulmonary hypertension leads to pulmonary
hypertension and right-sided heart failure. The purpose of this study was to investigate the efficacy …

[HTML][HTML] BMPR2 mutations and survival in pulmonary arterial hypertension: an individual participant data meta-analysis

…, LA Wheeler, I Nakayama, T Satoh… - The lancet Respiratory …, 2016 - thelancet.com
Background Mutations in the gene encoding the bone morphogenetic protein receptor type
II (BMPR2) are the commonest genetic cause of pulmonary arterial hypertension (PAH). …

Serum uric acid levels correlate with the severity and the mortality of primary pulmonary hypertension

N Nagaya, M Uematsu, T Satoh, S Kyotani… - American journal of …, 1999 - atsjournals.org
Serum uric acid (UA), the final product of purine degradation, has been proposed to be a
marker for impaired oxidative metabolism and a possible predictor of mortality in patients with …