Iron Oxide Decorated MoS2 Nanosheets with Double PEGylation for Chelator-Free Radiolabeling and Multimodal Imaging Guided Photothermal Therapy

…, L Cheng, C Wang, X Song, S Goel, TE Barnhart… - ACS …, 2015 - ACS Publications
Theranostics for in vivo cancer diagnosis and treatment generally requires well-designed
nanoscale platforms with multiple integrated functionalities. In this study, we uncover that …

Non-invasive multimodal functional imaging of the intestine with frozen micellar naphthalocyanines

…, H Hong, J Geng, Y Zhang, S Shi, TE Barnhart… - Nature …, 2014 - nature.com
There is a need for safer and improved methods for non-invasive imaging of the gastrointestinal
tract. Modalities based on X-ray radiation, magnetic resonance and ultrasound suffer …

In Vivo Tumor Targeting and Image-Guided Drug Delivery with Antibody-Conjugated, Radiolabeled Mesoporous Silica Nanoparticles

…, S Shi, GS Kwon, CP Theuer, TE Barnhart… - ACS …, 2013 - ACS Publications
Since the first use of biocompatible mesoporous silica (mSiO 2 ) nanoparticles as drug
delivery vehicles, in vivo tumor targeted imaging and enhanced anticancer drug delivery has …

Theranostic liposomes with hypoxia-activated prodrug to effectively destruct hypoxic tumors post-photodynamic therapy

L Feng, L Cheng, Z Dong, D Tao, TE Barnhart, W Cai… - ACS …, 2017 - ACS Publications
Photodynamic therapy (PDT), a noninvasive cancer therapeutic method triggered by light,
would lead to severe tumor hypoxia after treatment. Utilizing a hypoxia-activated prodrug, …

In Vivo Targeting and Imaging of Tumor Vasculature with Radiolabeled, Antibody-Conjugated Nanographene

…, TR Nayak, S Goel, J Bean, CP Theuer, TE Barnhart… - ACS …, 2012 - ACS Publications
Herein we demonstrate that nanographene can be specifically directed to the tumor
neovasculature in vivo through targeting of CD105 (ie, endoglin), a vascular marker for tumor …

Multifunctional unimolecular micelles for cancer-targeted drug delivery and positron emission tomography imaging

…, JW Engle, W Xu, Y Yang, Y Zhang, TE Barnhart… - Biomaterials, 2012 - Elsevier
A multifunctional unimolecular micelle made of a hyperbranched amphiphilic block copolymer
was designed, synthesized, and characterized for cancer-targeted drug delivery and non-…

[HTML][HTML] Engineering of hollow mesoporous silica nanoparticles for remarkably enhanced tumor active targeting efficacy

…, R Hernandez, CP Theuer, TE Barnhart… - Scientific reports, 2014 - nature.com
Hollow mesoporous silica nanoparticle (HMSN) has recently gained increasing interests due
to their tremendous potential as an attractive nano-platform for cancer imaging and therapy…

FeSe2‐Decorated Bi2Se3 Nanosheets Fabricated via Cation Exchange for Chelator‐Free 64Cu‐Labeling and Multimodal Image‐Guided Photothermal‐Radiation …

…, G Song, K Yang, G Liu, TE Barnhart… - Advanced functional …, 2016 - Wiley Online Library
Multifunctional theranostic agents have become rather attractive to realize image‐guided
combination cancer therapy. Herein, a novel method is developed to synthesize Bi 2 Se 3 …

In vivo targeting and positron emission tomography imaging of tumor vasculature with 66Ga-labeled nano-graphene

…, TR Nayak, CP Theuer, RJ Nickles, TE Barnhart… - Biomaterials, 2012 - Elsevier
The goal of this study was to employ nano-graphene for tumor targeting in an animal tumor
model, and quantitatively evaluate the pharmacokinetics and tumor targeting efficacy through …

[HTML][HTML] Molybdenum-based nanoclusters act as antioxidants and ameliorate acute kidney injury in mice

…, D Jiang, CJ Kutyreff, J Lai, Y Yan, TE Barnhart… - Nature …, 2018 - nature.com
Acute kidney injury (AKI) is a common reactive oxygen species (ROS)-related renal disease
that causes numerous deaths annually, yet only supportive treatment is currently available …