The human cerebral and systemic amyloidoses and prion-associated spongiform
encephalopathies are acquired or inherited protein folding disorders in which normally soluble …

The monoclonal antibody 2A4 binds an epitope derived from a cleavage site of serum amyloid
protein A (sAA) containing a -Glu-Asp- amino acid pairing. In addition to its reactivity with …

Heparan sulfate proteoglycans (HSPGs) are ubiquitous components of pathologic amyloid
deposits in the organs of patients with disorders such as Alzheimer's disease or systemic light …

Introduction Systemic amyloidosis is a progressive disorder characterized by the extracellular
deposition of amyloid fibrils and accessory proteins in visceral organs and tissues. …

Amyloid is a complex pathologic matrix comprised principally of paracrystalline protein
fibrils and heparan sulfate proteoglycans. Systemic amyloid diseases are rare, thus, routine …

Amyloidosis is a protein-misfolding disorder characterized by the extracellular deposition of
amyloid, a complex matrix composed of protein fibrils, hyper-sulphated glycosaminoglycans …

Background Systemic amyloidosis refers to a group of protein misfolding disorders
characterized by the extracellular deposition of amyloid fibrils in organs and tissues. For reasons …

Radioactive cadmium telluride/zinc sulfide (Cd 125m Te/ZnS) nanoparticles were targeted
to mouse lung with antibody to mouse lung endothelium and quantified using radiological …

Currently, there are no available means in the United States to document objectively the
location and extent of amyloid deposits in patients with systemic forms of amyloidosis. To …

Purpose I-labeled human serum amyloid P component (SAP) is used clinically only in the UK
for imaging visceral amyloidosis to assist with diagnosis, disease staging, and monitoring …