Labeling a Hydrazino Nicotinamide-Modified Cyclic IIb/IIIa Receptor Antagonist with 99mTc Using Aminocarboxylates as Coligands

…, JA Barrett, SJ Heminway, TR Carroll - Bioconjugate …, 1996 - ACS Publications
A series of 99m Tc complexes containing a hydrazinonicotinamide-conjugated cyclic IIb/IIIa
receptor antagonist, cyclo(d-Val-NMeArg-Gly-Asp-Mamb-(hydrazinonicotinyl-5-(6-…

New and versatile ternary ligand system for technetium radiopharmaceuticals: water soluble phosphines and tricine as coligands in labeling a hydrazinonicotinamide …

…, MC Ziegler, SJ Heminway, TR Carroll - Bioconjugate …, 1997 - ACS Publications
A hydrazinonicotinamide-functionalized cyclic platelet glycoprotein IIb/IIIa (GPIIb/IIIa)
receptor antagonist [cyclo(d-Val-NMeArg-Gly-Asp-Mamb(5-(6-(6-hydrazinonicotinamido)…

Labeling Cyclic Glycoprotein IIb/IIIa Receptor Antagonists with 99mTc by the Preformed Chelate Approach:  Effects of Chelators on Properties of [99mTc]Chelator …

…, M Rajopadhye, JP Bourque, TR Carroll - Bioconjugate …, 1996 - ACS Publications
Several cyclic GPIIb/IIIa receptor antagonists were labeled with 99m Tc by the preformed
chelate approach using chelators such as H 4 L1 [4,5-bis(mercaptoacetamido)pentanoic acid], …

Biological evaluation of thrombus imaging agents utilizing water soluble phosphines and tricine as coligands when used to label a hydrazinonicotinamide-modified …

…, M Kagan, TJ Mazaika, TR Carroll - Bioconjugate …, 1997 - ACS Publications
A hydrazinonicotinamide-functionalized cyclic glycoprotein IIb/IIIa (GPIIb/IIIa) receptor
antagonist [cyclo(d-Val-NMeArg-Gly-Asp-Mamb(5-(6-(6-hydrazinonicotinamido)hexanamide))) (…

Biological Evaluation of 99mTc-Labeled Cyclic Glycoprotein IIb/IIIa Receptor Antagonists in the Canine Arteriovenous Shunt and Deep Vein Thrombosis Models:  Effects of …

…, S Liu, DS Edwards, RJ Looby, TR Carroll - Bioconjugate …, 1996 - ACS Publications
… Bourque, Timothy R. Carroll. Synthesis and technetium-99m labeling of cyclic GP IIb/IIIa
receptor antagonists conjugated to 4,5-bis(mercaptoacetamido)-pentanoic acid (mapt). …

Tc-99m-labeled fibrinogen receptor antagonists: design and synthesis of cyclic RGD peptides for the detection of thrombi

…, J Lazewatsky, T Mazaika, TR Carroll - Bioorganic & Medicinal …, 1996 - Elsevier
Tc-99m labeled derivatives of N-Me-Arg-Gly-Asp containing cyclic peptide GP IIb/IIIa receptor
antagonists are potential radiopharmaceuticals for the diagnosis of thrombosis. The design …

Synthesis, evaluation and Tc-99m complexation of a hydrazinonicotinyl conjugate of a GP IIb/IIIa antagonist cyclic peptide for the detection of deep vein thrombosis

…, SJ Heminway, DS Edwards, TR Carroll - Bioorganic & Medicinal …, 1997 - Elsevier
A cyclic peptide GP IIb/IIIa receptor antagonist containing the N-Me-Arg-Gly-Asp motif has
been derivatized with the technetium chelating hydrazinonicotinyl group (Hynic). The Hynic …

The effect of selected preparation variables on the radiochemical purity of 99mTc-sestamibi

…, JL Born, TL Anderson, TR Carroll - Journal of nuclear …, 2005 - Soc Nuclear Med
Objective:Measurement of cardiac perfusion via agents such as 99m Tc-sestamibi (Cardiolite;
DuPont-Merck Pharmaceutical Co., Inc.) is widely used in clinical nuclear medicine for the …

[PDF][PDF] Autoradiography and radioscintigraphy of technetium-99m-sestamibi in c-neu transgenic mice

…, L Villamil-Perez, TR Carroll - Journal of Nuclear …, 1995 - Soc Nuclear Med
… Lazewatsky, Laura Villamil-Perez and Timothy R. Carroll … Tse N, Hoh C, Hawkins R.
The application of PET imaging with fluorode oxyglucoseto the evaluationof breast disease.Ann …

Synthesis and technetium-99m labeling of cyclic GP IIb/IIIa receptor antagonists conjugated to 4, 5-bis (mercaptoacetamido)-pentanoic acid (mapt)

…, DS Edwards, JP Bourque, TR Carroll - Bioorganic & Medicinal …, 1996 - Elsevier
The synthesis of cyclic Arg-Gly-Asp GP IIb/IIIa receptor antagonists conjugated to 4,5-bis(S-1-ethoxyethyl-mercaptoacetamido)pentanoic
acid is reported. The corresponding Tc-99m-…