To define predictors of survival time in late human immunodeficiency virus type 1 (HIV-1)
disease, long- and short-duration survivors were studied after their CD4 + T cells fell to ⩽50/mm …

Assessment of radiation and chemotherapy efficacy for brain cancer patients is traditionally
accomplished by measuring changes in tumor size several months after therapy has been …

Chronic obstructive pulmonary disease (COPD) is increasingly being recognized as a highly
heterogeneous disorder, composed of varying pathobiology. Accurate detection of COPD …

Purpose: Development of new therapeutic drug delivery systems is an area of significant
research interest. The ability to directly target a therapeutic agent to a tumor site would minimize …

Intraoperative diagnosis is essential for providing safe and effective care during cancer
surgery 1 . The existing workflow for intraoperative diagnosis based on hematoxylin and eosin …

Conventional methods for intraoperative histopathologic diagnosis are labour- and time-intensive,
and may delay decision-making during brain-tumour surgery. Stimulated Raman …

Background Obesity is a chronic disease that has become one of the most serious health
problems in Western society. Objective We assessed the long-term effects of an energy-…

Objective: To investigate the contribution of meal and snack replacements for long‐term
weight maintenance and risk factor reduction in obese patients. Research Methods and …

Diffuse malignant gliomas, the most common type of brain tumor, carry a dire prognosis and
are poorly responsive to initial treatment. The response to treatment is typically evaluated by …

The passage of the Best Pharmaceuticals for Children Act and the Pediatric Research
Equity Act has collectively resulted in an improvement in rational prescribing for children, …