[HTML][HTML] The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis

…, A Babelova, N Gretz, T Spieker… - The Journal of …, 2010 - Am Soc Clin Investig
CXCL13 is a key B cell chemoattractant and marker of disease activity in patients with SLE;
however, the mechanism of its induction has not been identified yet. Here, we have shown …

[HTML][HTML] The long noncoding MALAT-1 RNA indicates a poor prognosis in non-small cell lung cancer and induces migration and tumor growth

LH Schmidt, T Spieker, S Koschmieder… - Journal of thoracic …, 2011 - Elsevier
Introduction: The functions of large noncoding RNAs (ncRNAs) have remained elusive in
many cases. Metastasis-Associated-in-Lung-Adenocarcinoma-Transcript-1 (MALAT-1) is an …

Clonal deleterious mutations in the IκBα gene in the malignant cells in Hodgkin's lymphoma

…, A Staratschek-Jox, A Bräuninger, T Spieker… - The Journal of …, 2000 - rupress.org
Members of the nuclear factor (NF)-κB family of transcription factors play a crucial role in
cellular activation, immune responses, and oncogenesis. In most cells, they are kept inactive in …

[HTML][HTML] EBV-infected B cells in infectious mononucleosis: viral strategies for spreading in the B cell compartment and establishing latency

J Kurth, T Spieker, J Wustrow, JG Strickler… - Immunity, 2000 - cell.com
Infection of humans with Epstein-Barr virus (EBV) may cause infectious mononucleosis (IM).
Analysis of single EBV-infected cells from tonsils of IM patients for rearranged …

Differentiation of malignant and benign cardiac tumors using 18F-FDG PET/CT

…, L Stegger, A Hoffmeier, T Spieker… - Journal of Nuclear …, 2012 - Soc Nuclear Med
In the diagnostic algorithm of cardiac tumors, the noninvasive determination of malignancy
and metastatic spread is of major interest to stratify patients and to select and monitor …

[HTML][HTML] PD-1 and PD-L1 expression in NSCLC indicate a favorable prognosis in defined subgroups

…, E Wardelmann, C Müller-Tidow, T Spieker… - PloS one, 2015 - journals.plos.org
Background Immunotherapy can become a crucial therapeutic option to improve prognosis
for lung cancer patients. First clinical trials with therapies targeting the programmed cell …

Primary central nervous system lymphomas are derived from germinal-center B cells and show a preferential usage of the V4–34 gene segment

…, R Küppers, D Schlüter, T Spieker… - The American journal of …, 1999 - Elsevier
Primary central nervous system lymphomas (PCNSLs) have recently received considerable
clinical attention due to their increasing incidence. To clarify the histogenetic origin of these …

Survival and Clonal Expansion of Mutating “Forbidden”(Immunoglobulin Receptor–deficient) Epstein-Barr Virus–infected B Cells in Angioimmunoblastic T Cell …

A Bräuninger, T Spieker, K Willenbrock… - The Journal of …, 2001 - rupress.org
Angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) is a peculiar T cell
lymphoma, as expanding B cell clones are often present besides the malignant T cell clones. In …

Adhesion molecules involved in neutrophil recruitment during sepsis-induced acute kidney injury

JM Herter, J Rossaint, T Spieker… - Journal of innate immunity, 2014 - karger.com
Acute kidney injury (AKI) is a common complication in critically ill patients and is associated
with high mortality. Recruitment of neutrophils is a hallmark in the pathogenesis of AKI. …

Electrophysiological characteristics of ventricular tachyarrhythmias in cardiac sarcoidosis versus arrhythmogenic right ventricular cardiomyopathy

…, K Wasmer, S Zellerhoff, C Pott, J Köbe, T Spieker… - Heart Rhythm, 2013 - Elsevier
BACKGROUND: Recent evidence suggests that cardiac sarcoidosis (CS) and arrhythmogenic
right ventricular cardiomyopathy (ARVC) can manifest very similarly. OBJECTIVE: To …