Kinetic and Static Analysis of Poly-(Adenosine Diphosphate-Ribose) Polymerase-1–Targeted 18F-Fluorthanatrace PET Images of Ovarian Cancer

…, AR Pantel, V Viswanath, TL Dominguez… - Journal of Nuclear …, 2022 - Soc Nuclear Med
The poly-(adenosine diphosphate-ribose) polymerase (PARP) family of proteins participates
in numerous functions, most notably the DNA damage response. Cancer vulnerability to …

[HTML][HTML] Magnesium in aging, health and diseases

M Barbagallo, N Veronese, LJ Dominguez - Nutrients, 2021 - mdpi.com
Several changes of magnesium (Mg) metabolism have been reported with aging, including
diminished Mg intake, impaired intestinal Mg absorption and renal Mg wasting. Mild Mg …

Bronchial reactivity and intracellular magnesium: a possible mechanism for the bronchodilating effects of magnesium in asthma

LJ Dominguez, M BARBAGALLO… - Clinical …, 1998 - portlandpress.com
1.Increased bronchial smooth muscle contractility with consequent bronchial hyperreactivity
are characteristic physiopathological events of asthma. Since magnesium intervenes in …

Cognitive deficits, changes in synaptic function, and brain pathology in a mouse model of normal aging

…, H Solanoy, H Ngu, BE Lauffer, HH Lin, SL Dominguez… - ENeuro, 2015 - eneuro.org
Age is the main risk factor for sporadic Alzheimer’s disease. Yet, cognitive decline in aged
rodents has been less well studied, possibly due to concomitant changes in sensory or …

[HTML][HTML] Investigating cortical inhibition in first-degree relatives and probands in schizophrenia

N Radhu, LG Dominguez, TA Greenwood, F Farzan… - Scientific reports, 2017 - nature.com
Deficits in GABAergic inhibitory neurotransmission are a reliable finding in schizophrenia (SCZ)
patients. Previous studies have reported that unaffected first-degree relatives of patients …

Prediction of Neonatal Outcomes Using Gestational Age or Diagnosis of Severe Preeclampsia vs. HELLP Syndrome: A Case-Only Analysis

I HAUPTMAN, LIM Tiffany, ML WILSON - 2024 - researchsquare.com
Purpose: Hypertensive disorders of pregnancy cause significant neonatal complications.
Disease severity is often used to predict neonatal outcomes, however gestational age (GA) at …

[HTML][HTML] EGFR inhibitor erlotinib delays disease progression but does not extend survival in the SOD1 mouse model of ALS

CE Le Pichon, SL Dominguez, H Solanoy, H Ngu… - PloS one, 2013 - journals.plos.org
<p>Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that causes
progressive paralysis due to motor neuron death. Several lines of published evidence …

[HTML][HTML] BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and rats

M Weber, T Wu, WJ Meilandt, SL Dominguez… - Scientific Reports, 2017 - nature.com
Assessing BACE1 (β-site APP cleaving enzyme 1) knockout mice for general health and
neurological function may be useful in predicting risks associated with prolonged …

Magnesium role in health and longevity

M Barbagallo, LJ Dominguez - Trace elements and minerals in health and …, 2018 - Springer
Reduced Magnesium (Mg) Magnesium (Mg) intake is Longevity a frequent cause of Mg
Magnesium (Mg) deficit with age. A decreased intestinal Mg Magnesium (Mg) absorption and …

2012 Survey of States: Successes and Challenges during a Time of Change.

…, SS Lazarus, ML Thurlow, LM Dominguez - National Center on …, 2013 - ERIC
This report summarizes the thirteenth survey of states by the National Center on Educational
Outcomes (NCEO) at the University of Minnesota. Results are presented for 49 states and 6 …